Molecular radio-oncology[electronic ...
Baumann, Michael.

 

  • Molecular radio-oncology[electronic resource] /
  • 紀錄類型: 書目-電子資源 : Monograph/item
    杜威分類號: 616.994
    書名/作者: Molecular radio-oncology/ edited by Michael Baumann, Mechthild Krause, Nils Cordes.
    其他作者: Baumann, Michael.
    出版者: Berlin, Heidelberg : : Springer Berlin Heidelberg :, 2016.
    面頁冊數: ix, 201 p. : : ill. (some col.), digital ;; 24 cm.
    Contained By: Springer eBooks
    標題: Cancer - Molecular aspects.
    標題: Cancer - Radiotherapy.
    標題: Medicine & Public Health.
    標題: Oncology.
    標題: Imaging / Radiology.
    標題: Molecular Medicine.
    標題: Cancer Research.
    ISBN: 9783662496510
    ISBN: 9783662496497
    內容註: Molecular Radiobiology: Hypoxia -- Molecular Targeting of Growth Factor Receptor Signaling -- Molecular Targeting of Cell Adhesion Molecules -- Tumor Pathophysiology -- DNA Repair -- Cancer Stem Cells -- Normal Tissue. Biomarkers/Personalized Radiation Oncology: EGFR and other RTKs -- HPV -- Hypoxia -- Study design for Biomarker research in radiation oncology -- Gene expression/system biology. Molecular Imaging in Radiation Oncology:FMISO as a biomarker for clinical radiation oncology -- FDG and beyond -- Molecular imaging techniques beyond PET.
    摘要、提要註: This book concisely reviews our current understanding of hypoxia, molecular targeting, DNA repair, cancer stem cells, and tumor pathophysiology, while also discussing novel strategies for putting these findings into practice in daily clinical routine. Radiotherapy is an important part of modern multimodal cancer treatment, and the past several years have witnessed not only substantial improvements in radiation techniques and the use of new beam qualities, but also major strides in our understanding of molecular tumor biology and tumor radiation response. Against this backdrop, the book highlights recent efforts to identify reasonable and clinically applicable biomarkers using broad-spectrum tissue microarrays and high-throughput systems biology approaches like genomics and epigenomics. In particular, it describes in detail how such molecular information is now being exploited for diagnostic imaging and imaging throughout treatment using the example of positron emission tomography. By discussing all these issues in the context of modern radiation oncology, the book provides a broad, up-to-date overview of the molecular aspects of radiation oncology that will hopefully foster its further optimization.
    電子資源: http://dx.doi.org/10.1007/978-3-662-49651-0
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