The epigenome and developmental orig...
Rosenfeld, Cheryl S.

 

  • The epigenome and developmental origins of health and disease[electronic resource] /
  • 紀錄類型: 書目-電子資源 : Monograph/item
    杜威分類號: 599.935
    書名/作者: The epigenome and developmental origins of health and disease/ edited by Cheryl S. Rosenfeld.
    其他作者: Rosenfeld, Cheryl S.
    出版者: Amsterdam : : Academic Press,, c2015.
    面頁冊數: 1 online resource (xvii, 542 p.) : : ill. (chielfly col.)
    標題: Epigenetics.
    標題: Developmental biology.
    標題: Diseases - Causes and theories of causation.
    標題: Medical genetics.
    標題: Human genome.
    標題: Disease susceptibility.
    標題: Epigenesis, Genetic.
    標題: Developmental Biology.
    標題: Genome, Human.
    標題: Disease Susceptibility.
    標題: Embryology.
    標題: Prenatal Exposure Delayed Effects.
    ISBN: 9780128013830 (electronic bk.)
    ISBN: 0128013834 (electronic bk.)
    ISBN: 9780128016725 (electronic bk.)
    書目註: Includes bibliographical references and index.
    內容註: The developmental origins of health and disease (DOHaD) concept : past, present, and future / Peter D. Gluckman, Tatjana Buklijas and Mark A. Hanson -- Historical perspective of developmental origins of health and diseasein humans / Lewis P. Rubin -- DOHaD and the periconceptional period, a critical window in time / Congshan Sun, Miguel A. Velazquez and Tom P. Fleming -- Introduction to epigenetic mechanisms : the probable common thread for various developmental origins of health and diseases effects / Martha Susiarjo -- Perinatal neurohormonal programming and endocrine disruption / Cheryl S. Rosenfeld -- Parental nutrition and developmental origins of health and disease / Miguel A. Velazquez, Congshan Sun and Tom P. Fleming -- Maternal prenatal stress and the developmental origins of mental health : the role of epigenetics / Kieran J. O'Donnell andVivette Glover -- Epigenetics in the developmental origin of cardiovascular disorders / Jeffrey S. Gilbert -- Developmental effects of endocrine-disrupting chemicals inthe ovary and on female fertility / Mehmet Uzumcu and Aparna Mahakali Zama -- Developmental and eipigenetic origins of male reproductive pathologies / Carlos Guerrero-Bosagna -- Developmental origins of childhood asthma and allergic conditions : is there evidence of epigenetic regulation? / Steve Turner -- Immune disorders, epigenetics, and the developmental origins of health and disease / Rodney R. Dietert and Amrie C. Grammer -- Neurobehavioral disorders and developmental origins of health and disease / Curt A. Sandman, Quetzal A. Class, Laura M. Glynn and Elysia Poggi Davis -- Metabolic disorders and developmental origins of health and disease / Sara E. Pinney --
    摘要、提要註: "The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or conversely promote the health of the offspring. This book mines the existing literature of a variety of disciplines, from toxicology to nutrition to epigenetics, to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and resulting deleterious phenotypic and physiological effects in our offspring. It is increasingly becoming apparent that even subtle changes in the mother's diet, stress, and exposure to low concentrations of toxic chemicals at levels deemed safe by the EPA and FDA, such as endocrine disrupting compounds (EDC), can dramatically impact the health of ourchildren, possibly leading to metabolic, cardiovascular, immunological, and neurobehavioral disorders, and increased risk of cancer, to list but a few examples. Importantly, the common thread of how in utero and postnatal environmental changes may lead to DOHaD effects is through various epigenetic changes. The Epigenome and Developmental Origins of Health and Disease is a unique resource not only for geneticists and epigeneticists, but also for toxicologists, obestetricians, gynecologists, neurobiologists, nutritionists, physiologists, and psychologists."--Page 4 of cover
    電子資源: click for full text
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