Epigenetic technological application...
Zheng, Y. George.

 

  • Epigenetic technological applications[electronic resource] /
  • Record Type: Electronic resources : Monograph/item
    [NT 15000414]: 572.8/65
    Title/Author: Epigenetic technological applications/ edited by Y. George Zheng.
    other author: Zheng, Y. George.
    Published: Amsterdam : : Academic Press,, c2015.
    Description: 1 online resource (xxiii, 491 p., [18] p. of plates) : : ill. (some col.)
    Subject: Epigenetics - Data processing.
    Subject: Epigenetics - Research
    Subject: Epigenomics.
    ISBN: 9780128010808 (electronic bk.)
    ISBN: 0128010800 (electronic bk.)
    [NT 15000227]: Includes bibliographical references and index.
    [NT 15000228]: The state of the art of epigenetic technologies -- Technologies for the measurement and mapping of genomic 5-methylcytosine and 5-hydroxymethylcytosine -- High-throughput sequencing-based mapping of cytosine modifications -- Application of mass spectrometry in translational epigenetics -- Techniques analyzing chromatin modifications at specific single loci -- Comprehensive analysis of mammalian linker-histone variants and their mutants -- Crystallography-based mechanistic insights into epigenetic regulation -- Chemical and genetic approaches to study histone modifications -- Peptide microarrays for profiling of epigenetic targets -- Current methods for methylome profiling -- Bioinformatics and biostatistics in mining epigenetic disease markers and targets -- Computational modeling to elucidate molecular mechanisms of epigenetic memory -- DNA methyltransferase inhibitors for cancer therapy -- Histone acetyltransferases: enzymes, assays, and inhibitors -- In vitro histone deacetylase activity screening: making a case for better assays -- Enzymatic assays of histone methyltransferase enzymes -- Histone methyltransferase inhibitors for cancer therapy -- Discovery of histone demethylase inhibitors -- Histone demethylases: background, purification, and detection -- Animal model study of epigenetic inhibitors -- Index.
    Online resource: click for full text
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