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Patho-epigenetics of infectious disease[electronic resource] /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
杜威分類號:	616.07
書名/作者:	Patho-epigenetics of infectious disease/ edited by Janos Minarovits, Hans Helmut Niller.
其他作者:	Minarovits, Janos.
出版者:	Cham : : Springer International Publishing :, 2016.
面頁冊數:	xv, 137 p. : : ill., digital ;; 24 cm.
Contained By:	Springer eBooks
標題:
標題:	Life Sciences.
標題:	Microbial Genetics and Genomics.
標題:	Infectious Diseases.
標題:	Molecular Medicine.
標題:	Virology.
標題:	Medical Microbiology.
ISBN:	9783319247380
ISBN:	9783319247366
摘要、提要註:	Epigenetic modification of cellular genomes is a fascinating means of regulating tissue- and cell type-specific gene expression in all developmental stages of the life of an organism. Carefully orchestrated processes, such as DNA methylation and a plenitude of specific histone modifications secure the faithful transmission of gene expression patterns to progeny cells. Upon chronic infection, the epigenetic cellular balance can become disrupted and, in the long run, through the epigenetic reprogramming of host cell genomes, contribute to the malignant conversion of formerly healthy cells, in many cases preceded by the establishment of an epigenetic field of cancerization. The present volume undertakes to highlight the interactions of infectious pathogens and their effector molecules with the epigenetic regulatory machinery of the cell. Clearly, the recent take-off of epigenetics research did not leave Research on Infectious Diseases and Infection-Associated Cancer untouched. This resulted in a great many of clinically relevant data on understanding the molecular mechanisms of chronic infectious disease. Infectious pathogen- and disease-specific epigenetic alterations are already being used for the early detection of malignant disease and for the prediction of chemotherapy resistance or response to treatment.
電子資源:	http://dx.doi.org/10.1007/978-3-319-24738-0

Patho-epigenetics of infectious disease[electronic resource] /
Patho-epigenetics of infectious disease[electronic resource] /edited by Janos Minarovits, Hans Helmut Niller. - Cham :Springer International Publishing :2016. - xv, 137 p. :ill., digital ;24 cm. - Advances in experimental medicine and biology,v.8790065-2598 ;. - Advances in experimental medicine and biology ;946..

Epigenetic modification of cellular genomes is a fascinating means of regulating tissue- and cell type-specific gene expression in all developmental stages of the life of an organism. Carefully orchestrated processes, such as DNA methylation and a plenitude of specific histone modifications secure the faithful transmission of gene expression patterns to progeny cells. Upon chronic infection, the epigenetic cellular balance can become disrupted and, in the long run, through the epigenetic reprogramming of host cell genomes, contribute to the malignant conversion of formerly healthy cells, in many cases preceded by the establishment of an epigenetic field of cancerization. The present volume undertakes to highlight the interactions of infectious pathogens and their effector molecules with the epigenetic regulatory machinery of the cell. Clearly, the recent take-off of epigenetics research did not leave Research on Infectious Diseases and Infection-Associated Cancer untouched. This resulted in a great many of clinically relevant data on understanding the molecular mechanisms of chronic infectious disease. Infectious pathogen- and disease-specific epigenetic alterations are already being used for the early detection of malignant disease and for the prediction of chemotherapy resistance or response to treatment.

ISBN: 9783319247380

Standard No.: 10.1007/978-3-319-24738-0doiSubjects--Topical Terms:

634837

LC Class. No.: QH450

Dewey Class. No.: 616.07

Patho-epigenetics of infectious disease[electronic resource] /
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