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Modified nucleic acids[electronic resource] /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
杜威分類號:	572.8
書名/作者:	Modified nucleic acids/ edited by Kazuhiko Nakatani, Yitzhak Tor.
其他作者:	Nakatani, Kazuhiko.
出版者:	Cham : : Springer International Publishing :, 2016.
面頁冊數:	x, 276 p. : : ill. (some col.), digital ;; 24 cm.
Contained By:	Springer eBooks
標題:	Nucleic acids.
標題:	Life Sciences.
標題:	Nucleic Acid Chemistry.
標題:	Cell Biology.
標題:	Biochemical Engineering.
ISBN:	9783319271118
ISBN:	9783319271095
內容註:	Emissive 5-Substituted Uridine Analogues -- Fluorescent purine nucleosides and their applications -- Thiazole orange-tethered nucleic acids and ECHO probes for fluorometric detection of nucleic acids -- Synthetic wavelength-shifting fluorescent probes of nucleic acids -- DNA Assisted Multichromophore Assembly -- Polymerase Synthesis of Base-Modified DNA -- Photo-cross-linking Reaction in Nucleic Acids - Chemistry and Applications -- Site-Directed Spin Labeling for EPR Studies of Nucleic Acids -- Non-Covalent Modification of Double Stranded DNA at the Mismatch and Bulged Site -- 2',4'-Bridged Nucleic Acids for Targeting Double-Stranded DNA -- Specific Recognition of Single Nucleotide by Alkylating Oligonucleotides and Sensing of 8-oxoguanine -- Genetic alphabet expansion by unnatural base pair creation and its application to high affinity DNA aptamers.
摘要、提要註:	This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.
電子資源:	http://dx.doi.org/10.1007/978-3-319-27111-8

Modified nucleic acids[electronic resource] /
Modified nucleic acids[electronic resource] /edited by Kazuhiko Nakatani, Yitzhak Tor. - Cham :Springer International Publishing :2016. - x, 276 p. :ill. (some col.), digital ;24 cm. - Nucleic acids and molecular biology,v.310933-1891 ;. - Nucleic acids and molecular biology ;v.29..

Emissive 5-Substituted Uridine Analogues -- Fluorescent purine nucleosides and their applications -- Thiazole orange-tethered nucleic acids and ECHO probes for fluorometric detection of nucleic acids -- Synthetic wavelength-shifting fluorescent probes of nucleic acids -- DNA Assisted Multichromophore Assembly -- Polymerase Synthesis of Base-Modified DNA -- Photo-cross-linking Reaction in Nucleic Acids - Chemistry and Applications -- Site-Directed Spin Labeling for EPR Studies of Nucleic Acids -- Non-Covalent Modification of Double Stranded DNA at the Mismatch and Bulged Site -- 2',4'-Bridged Nucleic Acids for Targeting Double-Stranded DNA -- Specific Recognition of Single Nucleotide by Alkylating Oligonucleotides and Sensing of 8-oxoguanine -- Genetic alphabet expansion by unnatural base pair creation and its application to high affinity DNA aptamers.

This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.

ISBN: 9783319271118

Standard No.: 10.1007/978-3-319-27111-8doiSubjects--Topical Terms:

182751
Nucleic acids.

LC Class. No.: QP620

Dewey Class. No.: 572.8

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