Artificially controllable nanodevice...
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  • Artificially controllable nanodevices constructed by DNA origami technology[electronic resource] :photofunctionalization and single-molecule analysis /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 620.5
    書名/作者: Artificially controllable nanodevices constructed by DNA origami technology : photofunctionalization and single-molecule analysis // by Yangyang Yang.
    作者: Yang, Yangyang.
    出版者: Tokyo : : Springer Japan :, 2015.
    面頁冊數: xiii, 76 p. : : ill. (some col.), digital ;; 24 cm.
    Contained By: Springer eBooks
    標題: Nanostructures.
    標題: DNA.
    標題: Chemistry.
    標題: Nanochemistry.
    標題: Nanotechnology.
    標題: Biological Microscopy.
    標題: Spectroscopy and Microscopy.
    ISBN: 9784431557692
    ISBN: 9784431557685
    內容註: Introduction -- Direct observation of single hybridization and dissociation of photoresponsive oligonucleotides in the designed DNA nanostructure -- Direct observation of logic-gated dual-switching behaviors inducing the state transition in a DNA nanostructure -- Multi-directionally photo-controllable DNA nanostructure assembling reversibly in programmed patterns -- Arrangement of gold nanoparticles onto a slit-type DNA nanostructure in various patterns.
    摘要、提要註: In this book, the author deals mainly with two topics: (1) single-molecule visualization of switching behaviors in the DNA nanoframe system utilizing different kinds of molecular switches through the use of high-speed atomic force microscope (AFM); (2) construction of photocontrollable DNA nanostructures in programmed patterns and direct visualization of the dynamic assembling process. Here, high-speed AFM was employed to observe the dynamic movements of single molecules. Compared to a traditional single-molecule analysis method, such as fluorescence spectroscopy or electron microscopy, high-speed AFM makes possible the real-time observation of molecule behaviors. DNA nanostructures were designed and assembled as scaffolds to incorporate interested biomolecules. The observations were carried out under robust conditions without complicated pretreatment. Moreover, the photoresponsive molecules were successfully assembled into around 100 nm-sized DNA nanostructures. The assembly/disassembly of nanostructures can be regulated reversibly by photoirradiation. This book explains how DNA origami has gradually become a useful tool for the investigation of biochemical interactions in defined nanospace. It also shows the possibility of DNA nanostructures acting as nanodevices for application in biological systems, serving as a good introduction to basic DNA nanotechnology.
    電子資源: http://dx.doi.org/10.1007/978-4-431-55769-2
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