Medullary thyroid carcinoma[electron...
Raue, Friedhelm.

 

  • Medullary thyroid carcinoma[electronic resource] :biology, management, treatment /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 616.99444
    書名/作者: Medullary thyroid carcinoma : biology, management, treatment // edited by Friedhelm Raue.
    其他作者: Raue, Friedhelm.
    出版者: Cham : : Springer International Publishing :, 2015.
    面頁冊數: viii, 249 p. : : ill., digital ;; 24 cm.
    Contained By: Springer eBooks
    標題: Thyroid gland - Cancer.
    標題: Medicine & Public Health.
    標題: Oncology.
    標題: Endocrinology.
    標題: Human Genetics.
    標題: Nuclear Medicine.
    ISBN: 9783319225425
    ISBN: 9783319225418
    內容註: Thyroid C-Cell Biology and Oncogenic Transformation -- Histopathology of C cells and medullary thyroid carcinoma -- Epidemiology and clinical presentation of Medullary Thyroid Carcinoma -- Medullary thyroid carcinoma: Imaging -- Calcitonin as a Biomarker for Medullary Thyroid Carcinoma -- Hereditary Medullary Thyroid Cancer, Genotype phenotype correlation -- Pheochromocytomas in Multiple Endocrine Neoplasia 2 -- Primary hyperparathyroidism in Multiple Endocrine Neoplasia 2 Syndrome -- Surgical treatment of medullary thyroid carcinoma -- Long term follow up in medullary thyroid carcinoma -- Use of Tyrosine Kinase Inhibitors for Treatment of Medullary Thyroid Carcinoma.
    摘要、提要註: This book offers a comprehensive overview of medullary thyroid carcinoma, both in the more common sporadic form and in the familial form, multiple endocrine neoplasia (MEN) types 2A and 2B. The coverage includes, but is not limited to, molecular biology and genetics, pathology, clinical presentation, imaging techniques, surgical treatment, and follow-up. The role of calcitonin as a highly sensitive and specific tumor marker for the screening, diagnosis, and follow-up of MTC and metastatic disease is described, and the significance of other tumor markers is also considered. With regard to treatment, the use of thyroidectomy is fully discussed, including in children carrying the mutations in the RET proto-oncogene considered causative for MEN 2. Additionally, the value of tyrosine kinase inhibitors as the most effective treatment modality in patients with a large tumor burden or rapid tumor growth, or both, is explained. Medullary Thyroid Carcinoma and Multiple Endocrine Neoplasia Type 2 will be an ideal source of up-to-date information for a wide range of practitioners, including endocrinologists, oncologists, internal medicine specialists, geneticists, and nuclear medicine physicians.
    電子資源: http://dx.doi.org/10.1007/978-3-319-22542-5
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