The essential guide to N-of-1 trials...
Mitchell, Geoffrey.

 

  • The essential guide to N-of-1 trials in health[electronic resource] /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 615.1901
    書名/作者: The essential guide to N-of-1 trials in health/ edited by Jane Nikles, Geoffrey Mitchell.
    其他作者: Nikles, Jane.
    出版者: Dordrecht : : Springer Netherlands :, 2015.
    面頁冊數: xi, 245 p. : : ill., digital ;; 24 cm.
    Contained By: Springer eBooks
    標題: Drugs - Testing.
    標題: Crossover trials.
    標題: Biomedicine.
    標題: Biomedicine general.
    標題: Pharmacotherapy.
    標題: Psychology, general.
    標題: Statistics for Life Sciences, Medicine, Health Sciences.
    標題: Pharmacy.
    ISBN: 9789401772006
    ISBN: 9789401771993
    內容註: Preface -- Introduction -- What are N-of-1 trials?- N-of-1 trials in the behavioural sciences -- N-of-1 trials in medical contexts -- Aggregated N-of-1 trials -- Methodological considerations for N-of-1 trials -- Randomization, allocation concealment and blinding -- Data collection and quality control -- Individual reporting of N-of-1 trials to patients and clinicians -- Assessing and reporting adverse events -- Research ethics and N-of-1 trials -- Statistical analysis of N-of-1 trials -- The economics of N-of-1 trials -- Reporting N-of-1 trials to professional audiences -- Single patient open trials -- Systematic review and meta-analysis using N-of-1 trials -- Where are N-of-1 trials headed? -- Index.
    摘要、提要註: N-of-1 trials, a type of individualized randomized controlled trial, are relevant to almost every discipline in medicine and psychology. They can tell the clinician with precision whether a treatment works in that individual, which distinguishes from the information available from most other trial designs. They have the potential to revolutionize the way clinical medicine is practiced. Whether you are a busy clinician, a researcher or a student, this book provides everything you need to know about N-of-1 trials. Written and edited by some of the world's leading experts on N-of-1 trials, the book presents state of the art knowledge about N-of-1 trials, with chapters on ethics, statistics, health economics, design, analysis and reporting, and more. Full of examples and well illustrated, it is a comprehensive compendium of issues surrounding the design, conduct, interpretation and implementation of N-of-1 trials in a health system.
    電子資源: http://dx.doi.org/10.1007/978-94-017-7200-6
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