Stem cells in modeling human genetic...
Okamoto, Oswaldo Keith.

 

  • Stem cells in modeling human genetic diseases[electronic resource] /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 616.042
    書名/作者: Stem cells in modeling human genetic diseases/ edited by Mayana Zatz, Oswaldo Keith Okamoto.
    其他作者: Zatz, Mayana.
    出版者: Cham : : Springer International Publishing :, 2015.
    面頁冊數: xii, 147 p. : : ill., digital ;; 24 cm.
    Contained By: Springer eBooks
    標題: Genetic disorders.
    標題: Multipotent stem cells.
    標題: Life Sciences.
    標題: Stem Cells.
    標題: Regenerative Medicine/Tissue Engineering.
    標題: Human Genetics.
    ISBN: 9783319183145
    ISBN: 9783319183138
    內容註: Modeling Fragile X Syndrome in Human Pluripotent Cells -- Induced Pluripotent Stem Cells in Familial Dilated Cardiomyopathy -- Induced Pluripotent Stem Cells and Amyotrophic Lateral Sclerosis -- IPS Cells and Spinocerebellar Ataxia -- Induced Pluripotent Stem Cells and Vascular Disease -- iPS Cells and Cardiomyopathies -- Cancer Stem Cells and Chemoresistance -- Stem Cells in Autism Spectrum Disorders.
    摘要、提要註: Using stem cells to investigate currently untreatable human genetic diseases is the focus of this book. Several applications of the Nobel-Prize winning, revolutionary iPS cell technology are explored in detail, including in schizophrenia, autism, Huntington's disease, Alzheimer's disease, spinocerebellar ataxia, medulloblastoma heterogeneity, progeria, age-related macular degeneration, and muscular dystrophy . The book is divided into seven sections, each composed of authoritative and detailed chapters. The first section provides a theoretical and practical overview of stem cells in disease modeling. The following sections divide stem cell applications into various classes of pathology- psychiatric disorders, neurodegenerative disease, neurogenesis-associated disorders, and laminopathies. Following these sections, the book discusses the future perspectives- and challenges- of iPS technology. Broad in scope and in audience, Stem Cells in Modeling Human Genetic Diseases for postgraduate students, scientists, and clinicians interested in applications of the rapidly developing field of stem cell research in disease modeling and drug development and its dynamic role within regenerative medicine.
    電子資源: http://dx.doi.org/10.1007/978-3-319-18314-5
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