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Bioisosteres in medicinal chemistry[...

Brown, Nathan.

Bioisosteres in medicinal chemistry[electronic resource] /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
杜威分類號:	615.19
書名/作者:	Bioisosteres in medicinal chemistry/ edited by Nathan Brown.
其他作者:	Brown, Nathan.
出版者:	Hoboken : : John Wiley & Sons,, 2012.
面頁冊數:	1 online resource.
標題:	Drugs - Design.
標題:	Pharmaceutical chemistry.
ISBN:	9783527654307 (electronic bk.)
ISBN:	3527654305 (electronic bk.)
ISBN:	9783527654338 (electronic bk.)
ISBN:	352765433X (electronic bk.)
ISBN:	9781280778537 (MyiLibrary)
ISBN:	1280778539 (MyiLibrary)
摘要、提要註:	Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologi.
電子資源:	http://onlinelibrary.wiley.com/book/10.1002/9783527654307

Bioisosteres in medicinal chemistry[electronic resource] /
Bioisosteres in medicinal chemistry[electronic resource] /edited by Nathan Brown. - Hoboken :John Wiley & Sons,2012. - 1 online resource. - Methods and principles in medicinal chemistry ;v. 54. - Methods and principles in medicinal chemistry ;v. 39..

Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologi.

ISBN: 9783527654307 (electronic bk.)Subjects--Topical Terms:

424032
Drugs
--Design.

LC Class. No.: RS420

Dewey Class. No.: 615.19

Bioisosteres in medicinal chemistry[electronic resource] /
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020 $a 1280778539 (MyiLibrary)
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245 0 0 $a Bioisosteres in medicinal chemistry $h [electronic resource] / $c edited by Nathan Brown.
260 $a Hoboken : $b John Wiley & Sons, $c 2012.
300 $a 1 online resource.
490 1 $a Methods and principles in medicinal chemistry ; $v v. 54
520 $a Written with the practicing medicinal chemist in mind, this is the first modern handbook to systematically address the topic of bioisosterism. As such, it provides a ready reference on the principles and methods of bioisosteric replacement as a key tool in preclinical drug development. The first part provides an overview of bioisosterism, classical bioisosteres and typical molecular interactions that need to be considered, while the second part describes a number of molecular databases as sources of bioisosteric identification and rationalization. The third part covers the four key methodologi.
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650 0 $a Pharmaceutical chemistry. $3 223006
700 1 $a Brown, Nathan. $3 624854
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830 0 $a Methods and principles in medicinal chemistry ; $v v. 39. $3 519037
856 4 0 $u http://onlinelibrary.wiley.com/book/10.1002/9783527654307

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