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I. General Principles of Molecular Cardiology -- Chapter 1:Biotechnology and Cardiovascular Medicine: Recombinant Protein Therapy (Hiroshi Ashikaga, Kenneth R. Chien) -- Chapter 2:Human Genome Project and Cardiovascular Disease Genes (CC Liew, Victor J. Dzau) -- Chapter 3:Model Organisms for Cardiac Disease Gene Discovery (Calum A. Macrae, Mark C. Fishman) -- Chapter 4:Generation and Cloning of Genetically Modified Animals (Leon J. DeWindt, Pieter A. Doevendans, Kenneth R. Chien) -- Chapter 5:Mouse Models of Human Cardiovascular Disease (Geir Christensen, Ju Chen, John Ross, Jr., Kenneth Chien) -- Chapter 6:Towards Stem Cell Therapy (Pieter A. Doevendans, Christine Mummery, Kenneth Chien) -- Chapter 7: Cardiovascular Signaling Pathways (Susan F. Steinberg, Michael Karin, Joan Heller Brown) -- Chapter 8:Genetic Approaches to Cardiovascular Disease (Carl J. Vaughan, Craig T. Basson) -- Chapter 9:Gene Transfer Approaches for Cardiovascular Disease (Elizabeth Nabel) -- II. Cardiac Development and Congenital Heart Disease -- Chapter 10:Cardiac Development and Congenital Heart Disease (Deepak Srivastava, Eric N. Olson) -- Chapter 11:Development of Pacemaking and Cardiac Conduction System Lineages (Robert G. Gourdie, Steven W. Kubalak, Terrence X. O₂Brien, Kenneth R. Chien, Takashi Mikawa) -- Chapter 12:Cardiac Laterality and Congenital Heart Disease (Pilar Ruiz-Lozano, Angel Raya, Kenneth R. Chien, Juan Carlos Izpisua-Belmonte) -- Chapter 13:Pharyngeal Apparatus and Cardiac Neural Crest Defects (Antonio Baldini) -- Chapter 14:Monogenic Causes of Congenital Heart Disease (Joachim P. Schmitt, Christine E. Seidman) -- III. Cardiac Muscle Diseases -- Chapter 15:Molecular Pathways for Cardiac Hypertrophy and Heart Failure Progression (Masahiko Hoshijima, Susumu Minamisawa, Hideo Yasukawa, Kenneth R. Chien) -- Chapter 16:Molecular Genetics of Inherited Cardiomyopathies (Christopher Semsarian, J.F. Seidman, and Christine E. Seidman) -- Chapter 17:Molecular Pathways for Dilated Cardiomyopathy (K. Campbell)Chapter -- 18:Excitability and Conduction (Michael J. Ackerman, David E. Clapham) -- Chapter 19:Cardiac Arrhythmias: Inherited Molecular Mechanisms (Steve A.N. Goldstein, Mark T. Keating, Michael C. Sanguinetti) -- IV. Atherogenesis -- Chapter 20:Inflammation and Immunity in Atherogenesis (Peter Libby, G̲ran K. Hansson and Jordan S. Pober) -- Chapter 21:Molecular Biology of Lipoproteins and Dyslipidemias (Sotirios Tsimikas, Vincent Mooser) -- Chapter 22:Lipoprotein Oxidation, Macrophages, Immunity and Atherogenesis (Sotirios Tsimikas, Christopher K. Glass, Daniel Steinberg and Joseph L. Witztum) -- Chapter 23:Cellular Cholesterol Metabolism in Health and Disease (Ira Tabas) -- V. Ischemic Diseases and Angiogenesis -- Chapter 24:Angiogenesis in Cardiovascular Disease (Karen S. Moulton, Judah Folkman) -- Chapter 25:Coronary Restenosis (Hiroshi Ashikaga, Ori Ben-Yehuda, Kenneth R. Chien) -- Chapter 26:Molecular Basis for the Potential Use of NMDA Receptor Open-Channel Blockers in the Treatment of Cerebral Ischemia and Other Brain Insults (Stuart A. Lipton, Stephen F. Heinemann) -- VI. Thrombosis -- Chapter 27:Platelets and Anti-Platelet Therapy in Cardiovascular Disease: Molecular Mechanisms (Ori Ben-Yehuda) -- Chapter 28:Blood Coagulation and Atherothrombosis (Hiroshi Ashikaga, Kenneth R. Chien) -- Chapter 29:Thrombosis and Thrombolytic Therapy (H.R. Lijnen, H. Pannekoek, J. Vermylen) -- VII. Hypertension -- Chapter 30:Molecular Targets of Antihypertensive Drug Therapy (Edwin W. Williems, Ahsan Husain, Robert M. Graham) -- Chapter 31:Mechanisms and Molecular Pathways in Hypertension (Roger Brown, John Mullins, David J. Webb) -- VIII. Environmental and Genetic Modifiers of Cardiovascular Disease -- Chapter 32:Molecular Biology of Transplantation and Xenotransplantation -- (Patrick Hildbrand, Daniel R. Salomon) -- Chapter 33:Viral Infections of the Heart (Kirk U. Knowlton, Herv̌ Duplain) -- IX. Glossary:Resources, Websites. |