Molecular mechanisms of adult stem c...
Clark Conference ((2005 :)

 

  • Molecular mechanisms of adult stem cell aging[electronic resource] /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 616/.02774
    書名/作者: Molecular mechanisms of adult stem cell aging/ volume editor, Karl Lenhard Rudolph.
    其他作者: Rudolph, K. Lenhard.
    團體作者: Clark Conference
    出版者: Basel : : S. Karger,, 2010
    面頁冊數: 1 online resource : : ill. (some col.)
    附註: A meeting report of the first international Else Kroner-Fresenius-Symposium on Adult Stem Cell Aging
    標題: Stem cells
    標題: Cells - Congresses. - Aging
    標題: Aging - Congresses. - Molecular aspects
    標題: Adult Stem Cells - Congresses. - physiology
    標題: Cell Aging - Congresses. - genetics
    標題: DNA Damage - Congresses. - physiology
    標題: Telomere - Congresses. - genetics
    ISBN: 9783805592444
    書目註: Includes bibliographical references and index.
    摘要、提要註: There is growing evidence that adult stem cells age. This process can result in alterations in the number and function of stem cells, leading to distinct phenotypic outcomes in different organ systems. This publication provides an outstanding overview of this emerging field.The molecular causes of stem cell aging remain to be defined. Stem cell aging can involve cell-intrinsic as well as cell-extrinsic alterations affecting the stem cell niche or the macroenvironment. Stem cells have a longer life span than other cell populations and retain a capacity to proliferate and differentiate in adult organs. The aging of adult stem cells plays a key role in the decline of organ maintenance and regenerative potential during aging and during the end stage of chronic diseases. In addition, it can contribute to stem cell transformation and carcinogenesis.Molecular Mechanisms of Adult Stem Cell Aging will appeal to scientists working in the fields such as stem cells, aging, regeneration and cancer. This subject matter should be of interest to physicians and scientists specializing in geriatric medicine, internal medicine, and surgery. It is also likely to be an invaluable resource for medical students and biologists who wish to enhance their understanding of molecular and stem cell biology.
    電子資源: http://content.karger.com/ProdukteDB/produkte.asp?Aktion=showproducts&searchWhat=books&searchParm=toc&ProduktNr=249607
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