Principles of nucleic acid structure...
Neidle, Stephen.

 

  • Principles of nucleic acid structure[electronic resource] /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 547/.596
    書名/作者: Principles of nucleic acid structure/ Stephen Neidle.
    作者: Neidle, Stephen.
    出版者: Amsterdam : : Elsevier ;, 2008.
    面頁冊數: xii, 289 p. : : ill. ;; 26 cm.
    標題: Nucleic acids.
    標題: Nucleic Acid Conformation.
    標題: Nucleic Acids - chemistry.
    標題: Acides nucl�eiques.
    ISBN: 9780123695079
    ISBN: 0123695074
    書目註: Includes bibliographical references and index.
    內容註: Methods for Studying Nucleic Acid Structure. -- The building-blocks of DNA and RNA. -- DNA Structure as Observed in Fibres and Crystals. -- DNA-DNA recognition: non-standard and higher-order DNA structures. -- Principles of small molecule-DNA Recognition. -- The RNA structural world. -- Principles of Protein-DNA Recognition.
    摘要、提要註: This unique and practical resource provides the most complete and concise summary of underlying principles and approaches to studying nucleic acid structure, including discussion of x-ray crystallography, NMR, molecular modelling, and databases. Its focus is on a survey of structures especially important for biomedical research and pharmacological applications. To aid novices, the book includes an introduction to technical lingo used to describe nucleic acid structure and conformations (roll, slide, twist, buckle, etc.). This completely updated edition features expanded coverage of the latest advances relevant to recognition of DNA and RNA by small molecules and proteins. In particular, the reader will find extensive new discussions on: RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA). This handy guide ends with a complete list of resources, including relevant online databases and software. * Completely updated with expanded discussion of topics such as RNA folding, ribosome structure and antibiotic interactions, DNA quadruplexes, DNA and RNA protein complexes, and short interfering RNA (siRNA) * Includes a complete list of resources, including relevant online databases and software * Defines technical lingo for novices.
    電子資源: An electronic book accessible through the World Wide Web; click for information
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