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Redox-active therapeutics[electronic resource] /

紀錄類型:	書目-電子資源 : Monograph/item
杜威分類號:	616.39
書名/作者:	Redox-active therapeutics/ edited by Ines Batinic-Haberle, Julio S. Reboucas, Ivan Spasojevic.
其他作者:	Reboucas, Julio S.
出版者:	Cham : : Springer International Publishing :, 2016.
面頁冊數:	xxx, 694 p. : : ill., digital ;; 24 cm.
Contained By:	Springer eBooks
標題:	Oxidative stress.
標題:	Pharmacology.
標題:	Life Sciences.
標題:	Oxidative Stress.
標題:	Enzymology.
標題:	Cancer Research.
ISBN:	9783319307053
ISBN:	9783319307039
摘要、提要註:	This essential volume comprehensively discusses redox-active therapeutics, focusing particularly on their molecular design, mechanistic, pharmacological and medicinal aspects. The first section of the book describes the basic aspects of the chemistry and biology of redox-active drugs and includes a brief overview of the redox-based pathways involved in cancer (such as the role of mitochondria, hydrogen peroxide and endogenous antioxidative defenses) and the medical aspects of redox-active drugs, assuming little in the way of prior knowledge. The second section encompasses several major classes of redox-active experimental therapeutics, which include porphyrins, salens, nitrones, and other metal-containing (e.g., Mn, Fe, Cu, Zn, Sb) drugs as either single compounds or formulations with nanomaterials and quantum dots. Subsequent sections and chapters describe more specialized aspects of redox-active therapeutics in clinical disorders, such as cancer, cardiovascular diseases, diabetes, central nervous system injuries, neurodegenerative diseases, pain, radiation injury and radioprotection (such as of brain, lungs, head and neck and erectile function) and neglected diseases (e.g., leishmaniasis) Numerous illustrations, tables and figures enhance and complement the text; extensive references to relevant literature are also included. Redox-Active Therapeutics is an invaluable addition to Springer's Oxidative stress in applied basic research and clinical practice series. It is essential reading for researchers, clinicians and graduate students interested in understanding and exploring the Redoxome--the organism redox network--as an emerging frontier in drug design, redox biology and medicine.
電子資源:	http://dx.doi.org/10.1007/978-3-319-30705-3

Redox-active therapeutics[electronic resource] /
Redox-active therapeutics[electronic resource] /edited by Ines Batinic-Haberle, Julio S. Reboucas, Ivan Spasojevic. - Cham :Springer International Publishing :2016. - xxx, 694 p. :ill., digital ;24 cm. - Oxidative stress in applied basic research and clinical practice,2197-7224. - Oxidative stress in applied basic research and clinical practice..

This essential volume comprehensively discusses redox-active therapeutics, focusing particularly on their molecular design, mechanistic, pharmacological and medicinal aspects. The first section of the book describes the basic aspects of the chemistry and biology of redox-active drugs and includes a brief overview of the redox-based pathways involved in cancer (such as the role of mitochondria, hydrogen peroxide and endogenous antioxidative defenses) and the medical aspects of redox-active drugs, assuming little in the way of prior knowledge. The second section encompasses several major classes of redox-active experimental therapeutics, which include porphyrins, salens, nitrones, and other metal-containing (e.g., Mn, Fe, Cu, Zn, Sb) drugs as either single compounds or formulations with nanomaterials and quantum dots. Subsequent sections and chapters describe more specialized aspects of redox-active therapeutics in clinical disorders, such as cancer, cardiovascular diseases, diabetes, central nervous system injuries, neurodegenerative diseases, pain, radiation injury and radioprotection (such as of brain, lungs, head and neck and erectile function) and neglected diseases (e.g., leishmaniasis) Numerous illustrations, tables and figures enhance and complement the text; extensive references to relevant literature are also included. Redox-Active Therapeutics is an invaluable addition to Springer's Oxidative stress in applied basic research and clinical practice series. It is essential reading for researchers, clinicians and graduate students interested in understanding and exploring the Redoxome--the organism redox network--as an emerging frontier in drug design, redox biology and medicine.

ISBN: 9783319307053

Standard No.: 10.1007/978-3-319-30705-3doiSubjects--Topical Terms:

428884
Oxidative stress.

LC Class. No.: RB170

Dewey Class. No.: 616.39

Redox-active therapeutics[electronic resource] /
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