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Progress in the chemistry of organic natural products.[electronic resource] /Volume 102

紀錄類型:	書目-電子資源 : Monograph/item
杜威分類號:	547
書名/作者:	Progress in the chemistry of organic natural products./ edited by A. Douglas Kinghorn ... [et al.].
其他作者:	Kinghorn, A. Douglas.
出版者:	Cham : : Springer International Publishing :, 2016.
面頁冊數:	v, 252 p. : : ill., digital ;; 24 cm.
Contained By:	Springer eBooks
標題:	Chemistry, Organic.
標題:	Natural products.
標題:	Chemistry.
標題:	Organic Chemistry.
標題:	Medicinal Chemistry.
標題:	Medical Biochemistry.
ISBN:	9783319331720
ISBN:	9783319331706
摘要、提要註:	The first contribution reviews the phytochemical, chemical, and biological literature on members of the ingenane class of diterpenoids from their first isolation in 1968 through 2015, highlighting unresolved issues both common to phorboids and specific to ingenol derivatives. The biogenesis of ingenol is discussed in the light of the Jakupovic proposal of a dissection between the formation of the macrocyclic Euphorbia diterpenoids and the phorboids, and the clinical development of ingenol mebutate is chronicled in the light of its "reverse-pharmacology" focus. The second contribution offers a comprehensive view of the chemical wealth and the taxonomic problems currently impeding chemical and biological investigations of the genus Laurencia. It addresses the botanical description and the growth and population dynamics of the genus, as well as its chemical diversity and ecological relations; the secondary metabolites as well as their sources of isolation; and finally the biological activity.
電子資源:	http://dx.doi.org/10.1007/978-3-319-33172-0

Progress in the chemistry of organic natural products.[electronic resource] /Volume 102
Progress in the chemistry of organic natural products.Volume 102[electronic resource] /edited by A. Douglas Kinghorn ... [et al.]. - Cham :Springer International Publishing :2016. - v, 252 p. :ill., digital ;24 cm. - Progress in the chemistry of organic natural products,1022191-7043 ;. - Progress in the chemistry of organic natural products ;99..

The first contribution reviews the phytochemical, chemical, and biological literature on members of the ingenane class of diterpenoids from their first isolation in 1968 through 2015, highlighting unresolved issues both common to phorboids and specific to ingenol derivatives. The biogenesis of ingenol is discussed in the light of the Jakupovic proposal of a dissection between the formation of the macrocyclic Euphorbia diterpenoids and the phorboids, and the clinical development of ingenol mebutate is chronicled in the light of its "reverse-pharmacology" focus. The second contribution offers a comprehensive view of the chemical wealth and the taxonomic problems currently impeding chemical and biological investigations of the genus Laurencia. It addresses the botanical description and the growth and population dynamics of the genus, as well as its chemical diversity and ecological relations; the secondary metabolites as well as their sources of isolation; and finally the biological activity.

ISBN: 9783319331720

Standard No.: 10.1007/978-3-319-33172-0doiSubjects--Topical Terms:

404127
Chemistry, Organic.

LC Class. No.: QD251.3

Dewey Class. No.: 547

Progress in the chemistry of organic natural products.[electronic resource] /Volume 102
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