The long and short non-coding RNAs i...
Song, Erwei.

 

  • The long and short non-coding RNAs in cancer biology[electronic resource] /
  • 紀錄類型: 書目-電子資源 : Monograph/item
    杜威分類號: 616.994042
    書名/作者: The long and short non-coding RNAs in cancer biology/ edited by Erwei Song.
    其他作者: Song, Erwei.
    出版者: Singapore : : Springer Singapore :, 2016.
    面頁冊數: viii, 458 p. : : ill., digital ;; 24 cm.
    Contained By: Springer eBooks
    標題: Cancer - Genetic aspects.
    標題: Cancer genes.
    標題: Biomedicine.
    標題: Cancer Research.
    標題: Cell Biology.
    ISBN: 9789811014987
    ISBN: 9789811014963
    內容註: Non-coding RNAs: New Players in Cancers -- The Working Modules of Long Non-coding RNAs in Cancer Cells -- Methods to Study Long Non-coding RNA Biology in Cancer -- Relationship between Non-coding RNA Dysregulation and Epigenetic Mechanisms in Cancer -- Non-coding RNAs in Growth and Death of Cancer Cells -- Non-coding RNAs in Cancer Cell Plasticity -- Non-coding RNAs in Regulation of Cancer Metabolic Reprogramming -- Non-coding RNAs in Tumor Angiogenesis -- Non-coding RNAs in Cancer Immunity -- Non-coding RNAs in Therapeutic Resistance of Cancer -- Non-coding RNAs Regulating Cancer Signaling Network -- Non-coding RNAs Regulating NFkB Signaling -- Non-coding RNAs Regulating p53 and c-Myc Signaling -- Viral Non-coding RNAs in Cancer Biology -- Non-coding RNAs in Cancer Diagnosis -- Therapeutic Potentials of Non-coding RNAs: Targeted Delivery of NcRNAs in Cancer Cells.
    摘要、提要註: The book conveys a comprehensive knowledge of long and short ncRNAs in cancer regulation and their potentials as diagnostic biomarkers and therapeutic targets. Topics covered include the molecular mechanisms of various classes of ncRNAs (with emphasis on long non-coding RNAs and microRNAs) in cancer, the functional roles of ncRNAs in regulating different cancer hallmarks (including proliferation, apoptosis, stem-cell properties, epithelial-mesenchymal transition, metabolism, angiogenesis, tumor-host interactions and therapeutic resistance), the role of ncRNAs in regulating cancer signaling circuitry programs (highlighting their involvement in c-myc, p53 and NFkB signaling), a systemic summary of clinical and preclinical studies that evaluate the potential of ncRNA signatures for cancer diagnosis and prognosis and strategies to delivery short ncRNAs as therapeutic molecules for cancer treatment. This book may serve as a comprehensive resource for researchers, graduate students and oncologists in ncRNA and cancer research and help drug development by identifying ncRNA targets.
    電子資源: http://dx.doi.org/10.1007/978-981-10-1498-7
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