C-type lectin receptors in immunity[...
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  • C-type lectin receptors in immunity[electronic resource] /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 572.69
    書名/作者: C-type lectin receptors in immunity/ edited by Sho Yamasaki.
    其他作者: Yamasaki, Sho.
    出版者: Tokyo : : Springer Japan :, 2016.
    面頁冊數: vi, 215 p. : : ill., digital ;; 24 cm.
    Contained By: Springer eBooks
    標題: Lectins.
    標題: Cellular immunity.
    標題: Biomedicine.
    標題: Immunology.
    標題: Biochemistry, general.
    標題: Pharmaceutical Sciences/Technology.
    ISBN: 9784431560159
    ISBN: 9784431560135
    內容註: Part 1 ITAM-coupled Activating Receptors -- 1 Dectin-2 in anti-microbial immunity and homeostasis -- 2 The function of Mincle as a danger sensor -- 3 The DAP12-Associated Myeloid C-type Lectin 5A (CLEC5A) -- Part 2 HemITAM-bearing Receptors -- 4 Dectin-1 (CLEC7A, BGR, CLECSF12) -- 5 DNGR-1, an F-actin-binding C-type lectin receptor involved in cross-presentation of dead cell-associated antigens by dendritic cells -- 6 C-type lectin-like receptor 2 (CLEC-2) -- Part 3 ITIM-bearing Receptors -- 7 Dendritic cell immunoreceptor (DCIR): An ITIM-harboring C-type lectin receptor -- 8 Regulation and Function of the Inhibitory C-type Lectin Clec12A/MICL -- Part 4 Other receptors and related topics -- 9 DC-SIGN in infection and immunity -- 10 LOX-1 and immunity -- 11 MGL/CD301 as a unique C-type lectin expressed on dendritic cells and macrophages -- 12 Structural aspects of C-type lectin receptors -- 13 The Ligands of C-Type Lectins.
    摘要、提要註: The book presents the latest findings on C-type lectin receptors, focusing on individual receptors and their signaling. In recent years there have been great advances in the understanding of the function of these receptors as a newly emerging family of pattern-recognition receptors (PRRs) for pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) Comprising four parts: ITAM-coupled Activating Receptors; HemITAM-bearing Receptors; ITIM-bearing Receptors; and Other Receptors and Related Topics, this comprehensive review covers a broad range of C-type lectin receptors. The updated information on C-type lectin receptors and their ligands provided will appeal to a wide readership, from basic immunologists to physicians and surgeons. In addition, sections on novel drug development make this a valuable resource for pharmaceutical scientists.
    電子資源: http://dx.doi.org/10.1007/978-4-431-56015-9
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