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Dopamine action on behavioral response and medial amygdala neural response to chemosensory communication signals in male mice.

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
書名/作者:	Dopamine action on behavioral response and medial amygdala neural response to chemosensory communication signals in male mice.
作者:	Simonton, Ariel R.
面頁冊數:	55 p.
附註:	Source: Masters Abstracts International, Volume: 55-02.
Contained By:	Masters Abstracts International55-02(E).
標題:	Neurosciences.
標題:	Biology.
標題:	Communication.
ISBN:	9781339078588
摘要、提要註:	Chemical signals are an important mode of communication and behavior regulation in many mammalian species. Non-volatile signals are sent by one animal and received by a second animal, typically of the same species. They are detected by the vomeronasal organ, which transmits information through the accessory olfactory bulb to the medial amygdala. Within the medial amygdala, non-volatile odors are categorized based on the behavioral relevance to the receiver. Non-relevant biological odors activate only the anterior medial amygdala, whereas relevant biological odors activate both the anterior and posterior medial amygdala. The main intercalated nucleus, which lies adjacent to the medial amygdala, contains inhibitory GABA-ergic neurons, is activated by non-relevant odors, and may be responsible for suppressing posterior medial amygdala response to those odors. Intercalated cell groups are known to be inhibited by dopamine meaning the main intercalated nucleus may be involved in categorization through the effects of dopamine at the D1 receptor. The experiments presented here investigate the roles of the main intercalated nucleus, dopamine, and learning on medial amygdala activity in mice.
電子資源:	http://pqdd.sinica.edu.tw/twdaoapp/servlet/advanced?query=1600082

Dopamine action on behavioral response and medial amygdala neural response to chemosensory communication signals in male mice.
Simonton, Ariel R.

Dopamine action on behavioral response and medial amygdala neural response to chemosensory communication signals in male mice. - 55 p.

Source: Masters Abstracts International, Volume: 55-02.

Thesis (M.S.)--The Florida State University, 2015.

Chemical signals are an important mode of communication and behavior regulation in many mammalian species. Non-volatile signals are sent by one animal and received by a second animal, typically of the same species. They are detected by the vomeronasal organ, which transmits information through the accessory olfactory bulb to the medial amygdala. Within the medial amygdala, non-volatile odors are categorized based on the behavioral relevance to the receiver. Non-relevant biological odors activate only the anterior medial amygdala, whereas relevant biological odors activate both the anterior and posterior medial amygdala. The main intercalated nucleus, which lies adjacent to the medial amygdala, contains inhibitory GABA-ergic neurons, is activated by non-relevant odors, and may be responsible for suppressing posterior medial amygdala response to those odors. Intercalated cell groups are known to be inhibited by dopamine meaning the main intercalated nucleus may be involved in categorization through the effects of dopamine at the D1 receptor. The experiments presented here investigate the roles of the main intercalated nucleus, dopamine, and learning on medial amygdala activity in mice.

ISBN: 9781339078588Subjects--Topical Terms:

372208
Neurosciences.

Dopamine action on behavioral response and medial amygdala neural response to chemosensory communication signals in male mice.
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245 1 0 $a Dopamine action on behavioral response and medial amygdala neural response to chemosensory communication signals in male mice.
300 $a 55 p.
500 $a Source: Masters Abstracts International, Volume: 55-02.
500 $a Adviser: Michael Meredith.
502 $a Thesis (M.S.)--The Florida State University, 2015.
520 $a Chemical signals are an important mode of communication and behavior regulation in many mammalian species. Non-volatile signals are sent by one animal and received by a second animal, typically of the same species. They are detected by the vomeronasal organ, which transmits information through the accessory olfactory bulb to the medial amygdala. Within the medial amygdala, non-volatile odors are categorized based on the behavioral relevance to the receiver. Non-relevant biological odors activate only the anterior medial amygdala, whereas relevant biological odors activate both the anterior and posterior medial amygdala. The main intercalated nucleus, which lies adjacent to the medial amygdala, contains inhibitory GABA-ergic neurons, is activated by non-relevant odors, and may be responsible for suppressing posterior medial amygdala response to those odors. Intercalated cell groups are known to be inhibited by dopamine meaning the main intercalated nucleus may be involved in categorization through the effects of dopamine at the D1 receptor. The experiments presented here investigate the roles of the main intercalated nucleus, dopamine, and learning on medial amygdala activity in mice.
520 $a Within the main intercalated nucleus different doses of the dopamine agonist (SKF-38393) lead to different activation depending on which odor was presented, however this activation was not correlated with medial amygdala activity. Instead, the dopamine agonist increased medial amygdala activity in a dose dependent, but not odor dependent, manner. Classical conditioning to change an odor's significance from non-relevant to relevant did not affect medial amygdala activity, although dopamine did blunt the effect of odor learning within the basolateral amygdala. Finally, both the dopamine agonist and antagonist (SCH-23390) disrupted the expected pattern of investigation of a novel non-relevant odor after habituation to a relevant odor.
520 $a These results suggest that dopamine may be involved in main intercalated nucleus activity and investigation of non-relevant odors, but the role of both dopamine and the intercalated nucleus in medial amygdala activation remains unclear.
590 $a School code: 0071.
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650 4 $a Communication. $3 179021
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