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Preventive and predictive genetics[electronic resource] :towards personalised medicine /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
杜威分類號:	615.7
書名/作者:	Preventive and predictive genetics : towards personalised medicine // edited by Godfrey Grech, Iris Grossman.
其他作者:	Grech, Godfrey.
出版者:	Cham : : Springer International Publishing :, 2015.
面頁冊數:	xx, 378 p. : : ill., digital ;; 24 cm.
Contained By:	Springer eBooks
標題:	Medical Education.
標題:	Systems Biology.
標題:	Human Genetics.
標題:	Pharmacology/Toxicology.
標題:	Drug Resistance.
標題:	Pharmacogenetics.
標題:	Genetic screening.
標題:	Personalized medicine.
標題:	Biomedicine.
標題:	Molecular Medicine.
ISBN:	9783319153445 (electronic bk.)
ISBN:	9783319153438 (paper)
內容註:	Introduction -- Preventive and Predictive Genetics: A perspective -- Roadmap to Drug Development Enabled by Pharmacogenetics -- Preventative and Predictive Genetics: Towards Personalised Medicine -- Pharmacokinetics and Pharmacogenetics: bringing the magic bullet closer to reality -- Pharmacogenetics of Adverse Drug Reactions -- Pharmacogenomics for haemoglobinopathies therapeutics -- Pharmacogenetics of Neurodegenerative Disorders -- Pharmacogenetics of asthma -- Pharmacogenetics and antineoplastic therapies -- Pharmacogenetics of coumarin anticoagulant therapy -- Implementation of Genomic Medicine: tools and challenges -- Ethical Considerations in the Genomic Era -- Index.
摘要、提要註:	Traditionally, medical research comprised of the identification of the pathological causes of a disease, its epidemiology and empirical investigation of treatment response. Intensive genetic research, marked by the completion of the human genome project in 2003, heralded a new era in medical research. While epidemiology and gross pathology are still mainstay useful tools, genetics and genomics have gradually been shown to increase the resolution of drug response research, showing great potential in also informing and identifying the role of genes and their encoded products in the pathophysiology of diseases. This information is already being applied in the prevention of illness, effective early diagnosis, better risk assessment (prognosis), as well as targeted effective and safe treatment allocation (prediction and monitoring) Genetic testing and genomics support personalised medicine by translating genome-based knowledge into clinical practice, offering enhanced benefit for patients and health-care systems at large. Current routine practice for diagnosing and treating patients is conducted by correlating parameters such as age, gender and weight with risks and expected treatment outcomes. In the new era of personalised medicine the healthcare provider is equipped with improved ability to prevent, diagnose, treat and predict outcomes on the basis of complex information sources, including genetic and genomic data. Targeted therapy and reliable prediction of expected outcomes offer patients access to better healthcare management, by way of identifying the therapies effective for the relevant patient group, avoiding prescription of unnecessary treatment and reducing the likelihood of developing adverse drug reactions.
電子資源:	http://dx.doi.org/10.1007/978-3-319-15344-5

Preventive and predictive genetics[electronic resource] :towards personalised medicine /
Preventive and predictive geneticstowards personalised medicine /[electronic resource] :edited by Godfrey Grech, Iris Grossman. - Cham :Springer International Publishing :2015. - xx, 378 p. :ill., digital ;24 cm. - Advances in predictive, preventive and personalised medicine,v.92211-3495 ;. - Advances in predictive, preventive and personalised medicine ;v.1..

Introduction -- Preventive and Predictive Genetics: A perspective -- Roadmap to Drug Development Enabled by Pharmacogenetics -- Preventative and Predictive Genetics: Towards Personalised Medicine -- Pharmacokinetics and Pharmacogenetics: bringing the magic bullet closer to reality -- Pharmacogenetics of Adverse Drug Reactions -- Pharmacogenomics for haemoglobinopathies therapeutics -- Pharmacogenetics of Neurodegenerative Disorders -- Pharmacogenetics of asthma -- Pharmacogenetics and antineoplastic therapies -- Pharmacogenetics of coumarin anticoagulant therapy -- Implementation of Genomic Medicine: tools and challenges -- Ethical Considerations in the Genomic Era -- Index.

Traditionally, medical research comprised of the identification of the pathological causes of a disease, its epidemiology and empirical investigation of treatment response. Intensive genetic research, marked by the completion of the human genome project in 2003, heralded a new era in medical research. While epidemiology and gross pathology are still mainstay useful tools, genetics and genomics have gradually been shown to increase the resolution of drug response research, showing great potential in also informing and identifying the role of genes and their encoded products in the pathophysiology of diseases. This information is already being applied in the prevention of illness, effective early diagnosis, better risk assessment (prognosis), as well as targeted effective and safe treatment allocation (prediction and monitoring) Genetic testing and genomics support personalised medicine by translating genome-based knowledge into clinical practice, offering enhanced benefit for patients and health-care systems at large. Current routine practice for diagnosing and treating patients is conducted by correlating parameters such as age, gender and weight with risks and expected treatment outcomes. In the new era of personalised medicine the healthcare provider is equipped with improved ability to prevent, diagnose, treat and predict outcomes on the basis of complex information sources, including genetic and genomic data. Targeted therapy and reliable prediction of expected outcomes offer patients access to better healthcare management, by way of identifying the therapies effective for the relevant patient group, avoiding prescription of unnecessary treatment and reducing the likelihood of developing adverse drug reactions.

ISBN: 9783319153445 (electronic bk.)

Standard No.: 10.1007/978-3-319-15344-5doiSubjects--Topical Terms:

464070
Medical Education.

LC Class. No.: RM301.3.G45

Dewey Class. No.: 615.7

Preventive and predictive genetics[electronic resource] :towards personalised medicine /
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