Asymmetric synthesis of bioactive la...
Doran, Robert.

 

  • Asymmetric synthesis of bioactive lactones and the development of a catalytic asymmetric synthesis of alpha-Aryl ketones[electronic resource] /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 547.2
    書名/作者: Asymmetric synthesis of bioactive lactones and the development of a catalytic asymmetric synthesis of alpha-Aryl ketones/ by Robert Doran.
    作者: Doran, Robert.
    出版者: Cham : : Springer International Publishing :, 2015.
    面頁冊數: xxi, 202 p. : : ill., digital ;; 24 cm.
    Contained By: Springer eBooks
    標題: Asymmetric synthesis.
    標題: Biosynthesis.
    標題: Ketones.
    標題: Chemistry.
    標題: Organic Chemistry.
    標題: Catalysis.
    標題: Medicinal Chemistry.
    ISBN: 9783319205441 (electronic bk.)
    ISBN: 9783319205434 (paper)
    摘要、提要註: This thesis addresses two fundamental areas in contemporary organic chemistry: synthesis of natural products and catalytic asymmetric synthesis. Firstly, a new methodology, developed by our research group, which allows the asymmetric synthesis of lactones, a structural unit ubiquitous in natural products, was utilised in the synthesis of a number of natural product analogues that showed significant biological activity. Secondly, the development of a catalytic asymmetric synthesis of a key structural motif present in a number of natural products and pharmaceuticals was accomplished. During the course of this work we discovered dual stereocontrol, which is significant because it allows the configuration of a new stereocentre to be controlled by a simple change of proton source.
    電子資源: http://dx.doi.org/10.1007/978-3-319-20544-1
評論
Export
取書館別
 
 
變更密碼
登入