RNA and DNA diagnostics[electronic r...
Barciszewski, Jan.

 

  • RNA and DNA diagnostics[electronic resource] /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 572.88
    書名/作者: RNA and DNA diagnostics/ edited by Volker A. Erdmann, Stefan Jurga, Jan Barciszewski.
    其他作者: Erdmann, Volker A.
    出版者: Cham : : Springer International Publishing :, 2015.
    面頁冊數: x, 349 p. : : ill., digital ;; 24 cm.
    Contained By: Springer eBooks
    標題: RNA.
    標題: DNA.
    標題: Biomedicine.
    標題: Human Genetics.
    標題: Nucleic Acid Chemistry.
    標題: Molecular Medicine.
    標題: Biotechnology.
    ISBN: 9783319173054 (electronic bk.)
    ISBN: 9783319173047 (paper)
    內容註: Electrochemical Biosensors for miRNA Detection -- Electrochemical Detection of RNA -- DNA and PNA probes for DNA Detection in Electroanalytical Systems -- DNA for Non-Nucleic Acid Sensing -- Aptamers in Oncotherapy -- Genotyping of Single Nucleotide Polymorphism -- Environmentally Responsive and Bright Fluorescent Probes Possessing Dansyl-modified Oligonucleotides under Hybridization of DNA and RNA -- Fluorescent Nucleic Acid Analogues in Research and Clinical Diagnostics -- Emergent Properties and Functions of Nanoconfined Nucleic Acid Architectures -- RNA and DNA Diagnostics on Microspheres: Current and Emerging Methods -- DNA and RNA Electronic Properties for Molecular Modifications and Environmental State Diagnostics -- Mechanochemical Sensing -- Microarrays as Research Tools and Diagnostic Devices -- Quadruplex Priming Amplification (QPA) for Nucleic Acid Diagnostics -- Single-molecule strategies for DNA and RNA diagnostics -- Detection and Assessment of microRNA Expression in Human Disease.
    摘要、提要註: The aim of molecular diagnostics is preferentially to detect a developing disease before any symptoms appear. There has been a significant increase, fueled by technologies from the human genome project, in the availability of nucleic acid sequence information for all living organisms including bacteria and viruses. When combined with a different type of instrumentation applied, the resulting diagnostics is specific and sensitive. Nucleic acid-based medical diagnosis detects specific DNAs or RNAs from the infecting organism or virus and a specific gene or the expression of a gene associated with a disease. Nucleic acid approaches also stimulate a basic science by opening lines of inquiry that will lead to greater understanding of the molecules at the center of life. One can follow Richard Feynman's famous statement "What I cannot create, I do not understand.".
    電子資源: http://dx.doi.org/10.1007/978-3-319-17305-4
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