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STAT inhibitors in cancer[electronic...

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STAT inhibitors in cancer[electronic resource] /

紀錄類型:	書目-電子資源 : Monograph/item
杜威分類號:	616.99404
書名/作者:	STAT inhibitors in cancer/ edited by Alister C. Ward.
其他作者:	Ward, Alister C.
出版者:	Cham : : Springer International Publishing :, 2016.
面頁冊數:	vii, 195 p. : : ill., digital ;; 24 cm.
Contained By:	Springer eBooks
標題:	Cancer - Molecular aspects.
標題:	Transcription factors.
標題:	Cellular signal transduction.
標題:	Biomedicine.
標題:	Cancer Research.
ISBN:	9783319429496
ISBN:	9783319429472
內容註:	STATs in Health and Disease -- STAT Proteins in Cancer -- Translating STAT Inhibitors from the Lab to the Clinic -- Historical Development of STAT3 Inhibitors and Early Results in Clinical Trials -- STAT3 Inhibitors in Cancer: A Comprehensive Update -- Targeting Upstream Janus Kinases -- Inhibitors of Upstream Inducers of STAT Activation.
摘要、提要註:	This volume, which includes contributions from leading scientists and clinicians in the field, provides definitive, state-of-the-art information on STAT inhibitors in a biological and clinical context. It gives an overview of the biology of the STAT family of transcription factors and their role in cancer etiology. Additionally, it describes the raft of therapeutic approaches being used to inhibit STATs in the context of various cancers, covering the full spectrum of therapeutic approaches to inhibiting STATs, and presenting emerging data from clinical trials.
電子資源:	http://dx.doi.org/10.1007/978-3-319-42949-6

STAT inhibitors in cancer[electronic resource] /
STAT inhibitors in cancer[electronic resource] /edited by Alister C. Ward. - Cham :Springer International Publishing :2016. - vii, 195 p. :ill., digital ;24 cm. - Cancer drug discovery and development,2196-9906. - Cancer drug discovery and development..

STATs in Health and Disease -- STAT Proteins in Cancer -- Translating STAT Inhibitors from the Lab to the Clinic -- Historical Development of STAT3 Inhibitors and Early Results in Clinical Trials -- STAT3 Inhibitors in Cancer: A Comprehensive Update -- Targeting Upstream Janus Kinases -- Inhibitors of Upstream Inducers of STAT Activation.

This volume, which includes contributions from leading scientists and clinicians in the field, provides definitive, state-of-the-art information on STAT inhibitors in a biological and clinical context. It gives an overview of the biology of the STAT family of transcription factors and their role in cancer etiology. Additionally, it describes the raft of therapeutic approaches being used to inhibit STATs in the context of various cancers, covering the full spectrum of therapeutic approaches to inhibiting STATs, and presenting emerging data from clinical trials.

ISBN: 9783319429496

Standard No.: 10.1007/978-3-319-42949-6doiSubjects--Topical Terms:

336981
Cancer
--Molecular aspects.

LC Class. No.: RC268.4

Dewey Class. No.: 616.99404

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520 $a This volume, which includes contributions from leading scientists and clinicians in the field, provides definitive, state-of-the-art information on STAT inhibitors in a biological and clinical context. It gives an overview of the biology of the STAT family of transcription factors and their role in cancer etiology. Additionally, it describes the raft of therapeutic approaches being used to inhibit STATs in the context of various cancers, covering the full spectrum of therapeutic approaches to inhibiting STATs, and presenting emerging data from clinical trials.
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