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MicroRNAs in malignant tumors of the skin[electronic resource] :first steps of tiny players in the skin to a new world of genomic medicine /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
杜威分類號:	616.99477042
書名/作者:	MicroRNAs in malignant tumors of the skin : first steps of tiny players in the skin to a new world of genomic medicine // by Michael Sand.
作者:	Sand, Michael.
出版者:	Wiesbaden : : Springer Fachmedien Wiesbaden :, 2016.
面頁冊數:	xi, 245 p. : : ill., digital ;; 24 cm.
Contained By:	Springer eBooks
標題:	Skin - Cancer
標題:	RNA.
標題:	Medicine & Public Health.
標題:	Dermatology.
標題:	Cancer Research.
標題:	Pathology.
ISBN:	9783658127947
ISBN:	9783658127930
內容註:	Introduction -- Objectives of this work -- Summary and discussion of this work -- Closing remarks -- Paper 1: Expression levels of the microRNA processing enzymes Drosha and Dicer in epithelial skin cancer -- Paper 2: Expression levels of the microRNA maturing microprocessor complex component DGCR8 and the RNA- induced silencing complex (RISC) components argonaute-1, argonaute-2, PACT, TARBP1 and TARBP2 in epithelial skin cancer -- Paper 3: Expression of microRNAs in basal cell carcinoma -- Paper 4: Microarray analysis of microRNA expression in cutaneous squamous cell carcinoma -- Paper 5: The miRNA machinery in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases and benign melanocytic nevi -- Paper 6: Immunohistochemical expression patterns of the microRNA-processing enzyme Dicer in cutaneous malignant melanomas, benign melanocytic nevi and dysplastic melanocytic nevi -- Paper 7: Comparative microarray analysis of microRNA expression profiles in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases and benign melanocytic nevi -- Paper 8: MicroRNAs and the skin: tiny players in the body's largest organ -- Paper 9: microRNA in non-melanoma skin cancer.
摘要、提要註:	Michael Sand gives the reader an overview of current techniques in expression profiling of miRNAs and their maturation machinery in the skin. This book is a postdoctoral thesis on miRNAs in cutaneous malignant melanoma and non-melanoma skin cancer with a focus on the miRNA processing machinery and miRNA expression profiling. The research presented in this book was performed in the Dermatologic Surgery Section at the Department of Dermatology, Venereology and Allergology of the Ruhr-University Bochum, Germany and gives the reader an overview of current techniques in expression profiling of miRNAs and their maturation machinery in the skin. Contents MicroRNAS Basal cell carcinoma Cutaneous squamous cell carcinoma Cutaneous malignant melanoma Target Groups Researchers and students in the field of medicine, dermatology, molecular biology, pathology Dermatologist and pathologist About the Author Michael Sand, MD studied medicine at the Ruhr-University of Bochum / Germany, Harvard Medical School Boston and the University of California, San Diego (UCSD) After board certification in Dermatology, Venereology and Emergency Medicine at the Ruhr-University Bochum / Germany he and his team started to investigate the role of microRNA in the skin. He is currently an attending physician in the Department of Plastic Surgery, Catholic Clinics of the Ruhr Peninsula, Essen, Germany with a clinical focus on surgical therapy of skin cancer and a research focus on the role of microRNAs in malignant skin tumors.
電子資源:	http://dx.doi.org/10.1007/978-3-658-12794-7

MicroRNAs in malignant tumors of the skin[electronic resource] :first steps of tiny players in the skin to a new world of genomic medicine /
Sand, Michael.

MicroRNAs in malignant tumors of the skinfirst steps of tiny players in the skin to a new world of genomic medicine /[electronic resource] :by Michael Sand. - Wiesbaden :Springer Fachmedien Wiesbaden :2016. - xi, 245 p. :ill., digital ;24 cm.

Introduction -- Objectives of this work -- Summary and discussion of this work -- Closing remarks -- Paper 1: Expression levels of the microRNA processing enzymes Drosha and Dicer in epithelial skin cancer -- Paper 2: Expression levels of the microRNA maturing microprocessor complex component DGCR8 and the RNA- induced silencing complex (RISC) components argonaute-1, argonaute-2, PACT, TARBP1 and TARBP2 in epithelial skin cancer -- Paper 3: Expression of microRNAs in basal cell carcinoma -- Paper 4: Microarray analysis of microRNA expression in cutaneous squamous cell carcinoma -- Paper 5: The miRNA machinery in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases and benign melanocytic nevi -- Paper 6: Immunohistochemical expression patterns of the microRNA-processing enzyme Dicer in cutaneous malignant melanomas, benign melanocytic nevi and dysplastic melanocytic nevi -- Paper 7: Comparative microarray analysis of microRNA expression profiles in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases and benign melanocytic nevi -- Paper 8: MicroRNAs and the skin: tiny players in the body's largest organ -- Paper 9: microRNA in non-melanoma skin cancer.

Michael Sand gives the reader an overview of current techniques in expression profiling of miRNAs and their maturation machinery in the skin. This book is a postdoctoral thesis on miRNAs in cutaneous malignant melanoma and non-melanoma skin cancer with a focus on the miRNA processing machinery and miRNA expression profiling. The research presented in this book was performed in the Dermatologic Surgery Section at the Department of Dermatology, Venereology and Allergology of the Ruhr-University Bochum, Germany and gives the reader an overview of current techniques in expression profiling of miRNAs and their maturation machinery in the skin. Contents MicroRNAS Basal cell carcinoma Cutaneous squamous cell carcinoma Cutaneous malignant melanoma Target Groups Researchers and students in the field of medicine, dermatology, molecular biology, pathology Dermatologist and pathologist About the Author Michael Sand, MD studied medicine at the Ruhr-University of Bochum / Germany, Harvard Medical School Boston and the University of California, San Diego (UCSD) After board certification in Dermatology, Venereology and Emergency Medicine at the Ruhr-University Bochum / Germany he and his team started to investigate the role of microRNA in the skin. He is currently an attending physician in the Department of Plastic Surgery, Catholic Clinics of the Ruhr Peninsula, Essen, Germany with a clinical focus on surgical therapy of skin cancer and a research focus on the role of microRNAs in malignant skin tumors.

ISBN: 9783658127947

Standard No.: 10.1007/978-3-658-12794-7doiSubjects--Topical Terms:

647406
Skin
--Cancer

LC Class. No.: RC280.S5

Dewey Class. No.: 616.99477042

MicroRNAs in malignant tumors of the skin[electronic resource] :first steps of tiny players in the skin to a new world of genomic medicine /
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