Immune responses to biosurfaces[elec...
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  • Immune responses to biosurfaces[electronic resource] :mechanisms and therapeutic interventions /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 612.015
    書名/作者: Immune responses to biosurfaces : mechanisms and therapeutic interventions // edited by John D. Lambris ... [et al.].
    其他作者: Lambris, J. D.
    出版者: Cham : : Springer International Publishing :, 2015.
    面頁冊數: xii, 242 p. : : ill., digital ;; 24 cm.
    Contained By: Springer eBooks
    標題: Biological interfaces - Congresses.
    標題: Immune response - Congresses. - Molecular aspects
    標題: Biomedicine.
    標題: Immunology.
    標題: Biotechnology.
    標題: Biomedical Engineering.
    ISBN: 9783319186030
    ISBN: 9783319186023
    內容註: Part 1. Mechanisms -- Thromboinflammation in Therapeutic Medicine -- Complement Interactions with Blood Cells, Endothelial Cells and Microvesicles in Thrombotic and Inflammatory Conditions -- Role of Complement on Broken Surfaces after Trauma -- Complement Involvement in Periodontitis: Molecular Mechanisms and Rational Therapeutic Approaches -- Part 2. Biomaterials -- The Lectin Pathway of Complement and Biocompatibility -- Foreign Body Reaction to Subcutaneous Implants -- Molecular Characterization of Macrophage-Biomaterial Interactions -- Heparan Sulfate Proteoglycan Metabolism and the Fate of Grafted Tissues -- Part 3. Transplantation -- Xenotransplantation of Cells, Tissues, Organs and the German Research Foundation Transregio Collaborative Research Centre 127 -- Macro encapsulated Pig Islets Correct Induced Diabetes in Primates up to 6 Months -- Regulation of Instant Blood Mediated Inflammatory Reaction (IBMIR) in Pancreatic Islet Xeno-Transplantation—Points for Therapeutic Interventions -- Cell Surface Engineering for Regulation of Immune Reactions in Cell Therapy -- Complement Interception Across Humoral Incompatibility in Solid Organ Transplantation-A Clinical Perspective.
    摘要、提要註: The collection of chapters in this proceedings volume brings together research from academic and industry scientists and clinical development experts who are focused on contemporary and emerging aspects of improving treatments employing biosurfaces. Interactions between biomaterial implants, devices, cell therapies, and whole organ transplants frequently trigger activation of body defense systems and responses that negatively affect the clinical outcome. Optimal tissue integration and modulation of foreign body reactions is therefore essential for preserving anticipated functions and avoiding adverse effects. Topics covered include mechanistic and applied research within the fields of extracorporeal devices, soft and hard tissue implants, tissue and biomaterial-targeting, therapeutic modulation of foreign body reactions, cell encapsulations, as well as cell and whole organ transplantation.
    電子資源: http://dx.doi.org/10.1007/978-3-319-18603-0
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