Real-time monitoring of cancer cell ...
Alborzinia, Hamed.

 

  • Real-time monitoring of cancer cell metabolism for drug testing[electronic resource] /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 615.7
    書名/作者: Real-time monitoring of cancer cell metabolism for drug testing/ by Hamed Alborzinia.
    作者: Alborzinia, Hamed.
    出版者: Wiesbaden : : Springer Fachmedien Wiesbaden :, 2015.
    面頁冊數: xiii, 153 p. : : ill., digital ;; 24 cm.
    Contained By: Springer eBooks
    標題: Drug monitoring.
    標題: Cisplatin.
    標題: Cancer cells - Treatment.
    標題: Biomedicine.
    標題: Cancer Research.
    標題: Pharmacology/Toxicology.
    標題: Medicinal Chemistry.
    ISBN: 9783658101619 (electronic bk.)
    ISBN: 9783658101602 (paper)
    內容註: Drug Screening with New Perspectives -- Real-Time Monitoring of Living Cells by a Novel Online Biosensor Chip -- Anticancer Agents – Effects Measured in Real Time -- Metabolism of Cancer Cells.
    摘要、提要註: Hamed Alborzinia uses the biosensor chip to monitor the metabolic and morphological changes in cancer cell lines in real time, particularly: (i) real-time measurements of basic cancer cell metabolism of different cancer cell lines; (ii) a detailed timeline of the metabolic response to cisplatin treatment and clear detection of the time span between start of cisplatin treatment and onset of cell death, which reflects the time required for the underlying molecular mechanisms of cell fate decision; (iii) direct functional measurement of the biological activity of a key regulatory protein of cellular metabolism following the kinetic change in respiration upon SIRT3 overexpression; and (iv) the time-resolved impact of several organometallic compounds on cell metabolism and cell morphology, including unexpected and not yet understood highly significant and specific effects on cell-cell interaction and adhesion. Contents Drug Screening with New Perspectives Real-Time Monitoring of Living Cells by a Novel Online Biosensor Chip Anticancer Agents – Effects Measured in Real Time Metabolism of Cancer Cells. Target Groups Researchers and students in the fields of biotechnology and pharmacy The Author Hamed Alborzinia graduated in veterinary medicine from Shiraz University (Iran) in 2005 and continued in the Ph.D. program, now as post-Doc, with Prof. Dr. Stefan Wolfl at Heidelberg University (IPMB), using bioanalytical techniques in research on cancer cell metabolism.
    電子資源: http://dx.doi.org/10.1007/978-3-658-10161-9
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