Cell signaling during mammalian earl...
Brison, Daniel R.

 

  • Cell signaling during mammalian early embryo development[electronic resource] /
  • 紀錄類型: 書目-電子資源 : Monograph/item
    杜威分類號: 573.619
    書名/作者: Cell signaling during mammalian early embryo development/ edited by Henry J. Leese, Daniel R. Brison.
    其他作者: Leese, Henry J.
    出版者: New York, NY : : Springer New York :, 2015.
    面頁冊數: xii, 216 p. : : ill., digital ;; 24 cm.
    Contained By: Springer eBooks
    標題: Mammals - Reproduction.
    標題: Embryos.
    標題: Cells.
    標題: Life Sciences.
    標題: Embryology.
    標題: Cell Biology.
    標題: Reproductive Medicine.
    ISBN: 9781493924806 (electronic bk.)
    ISBN: 9781493924790 (paper)
    摘要、提要註: The book considers signaling events from the zygote embryo through to the blastocyst with relevant data from embryonic stem (ES) cells, including dialogue with the extracellular environment and with the maternal tract during the implantation process. Application of the knowledge described to improve the success of human and animal assisted conception is considered where appropriate, but the focus is largely on fundamental rather than applied cell/molecular biology, as this is the area that has historically been neglected. While the general features of metabolism during preimplantation development are well established, especially in terms of nutrient requirements, uptake and fate, remarkably little is known about early embryo signaling events, intracellular or intercellular, between individual embryos in vitro or with the female reproductive tract in vivo. This contrasts with the wealth of information on cell signaling in somatic cells and tissues, as a glance at any textbook of biochemistry illustrates. This lack of information is such that our understanding of the molecular cell biology of early embryos -- a prerequisite to defining the mechanisms which regulate development at this critical stage of the life cycle -- is seriously incomplete. This volume is the first to address this issue by describing the current state of knowledge on cell signaling during mammalian early embryo development and highlighting priority areas for research.
    電子資源: http://dx.doi.org/10.1007/978-1-4939-2480-6
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