Applications of transition metal cat...
Crawley, Matthew L.

 

  • Applications of transition metal catalysis in drug discovery and development[electronic resource] :an industrial perspective /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 615.19
    書名/作者: Applications of transition metal catalysis in drug discovery and development : an industrial perspective // edited by Matthew L. Crawley, Barry M. Trost.
    其他作者: Crawley, Matthew L.
    出版者: Hoboken, N.J. : : John Wiley & Sons,, 2012.
    面頁冊數: 1 online resource (xviii, 356 p.)
    標題: Catalysis.
    標題: Transition metals.
    標題: Pharmacy.
    標題: Drug Discovery.
    標題: Pharmaceutical Preparations - chemistry.
    標題: Transition Elements.
    ISBN: 9781118309872 (electronic bk.)
    ISBN: 1118309871 (electronic bk.)
    ISBN: 9781118309865 (electronic bk.)
    ISBN: 1118309863 (electronic bk.)
    ISBN: 0470631325 (hbk.)
    ISBN: 9781280592386 (MyiLibrary)
    ISBN: 1280592389 (MyiLibrary)
    書目註: Includes bibliographical references and index.
    內容註: Applications of TRANSITION METAL CATALYSIS in Drug Discovery and Development; Contents; Preface; Contributors; About the Authors; 1 Transition Metal Catalysis in the Pharmaceutical Industry; 1.1 Overview of Catalysis; 1.2 Transition Metal Catalysis in the Pharmaceutical Industry; 1.2.1 Cross-Couplings for the Formation of Carbon-Carbon Bonds; 1.2.2 Cross-Couplings for the Formation of Carbon-Heteroatom Bonds; 1.2.3 Asymmetric Hydrogenation; 1.2.4 Oxidative Catalysis; 1.2.5 Asymmetric Addition Reactions; 1.2.6 Metathesis; 1.3 Challenges in Taking Catalysis to Industrial Scales
    摘要、提要註: "This book focuses on the drug discovery and development applications of transition metal catalyzed processes, which can efficiently create preclinical and clinical drug candidates as well as marketed drugs. The authors pay particular attention to the challenges of transitioning academically-developed reactions into scalable industrial processes. Additionally, the book lays the groundwork for how continued development of transition metal catalyzed processes can deliver new drug candidates. This work provides a unique perspective on the applications of transition metal catalysis in drug discovery and development."--Provided by publisher.
    電子資源: http://onlinelibrary.wiley.com/book/10.1002/9781118309872
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