Predicting transcription factor comp...
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  • Predicting transcription factor complexes[electronic resource] :a novel approach to data integration in systems biology /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 572.8845
    書名/作者: Predicting transcription factor complexes : a novel approach to data integration in systems biology // by Thorsten Will.
    作者: Will, Thorsten.
    出版者: Wiesbaden : : Springer Fachmedien Wiesbaden :, 2015.
    面頁冊數: xix, 142 p. : : ill., digital ;; 24 cm.
    Contained By: Springer eBooks
    標題: Transcription factors.
    標題: Genetic regulation.
    標題: Bioinformatics.
    標題: Proteins - Conformation.
    標題: Life Sciences.
    標題: Computer Appl. in Life Sciences.
    標題: Mathematical and Computational Biology.
    ISBN: 9783658082697 (electronic bk.)
    ISBN: 9783658082680 (paper)
    內容註: Protein Complex Prediction -- Protein-Protein Interaction Networks -- Domain-Domain Interaction Networks -- Combinatorial Algorithms -- Algorithm Engineering.
    摘要、提要註: In his master thesis Thorsten Will proposes the substantial information content of protein complexes involving transcription factors in the context of gene regulatory networks, designs the first computational approaches to predict such complexes as well as their regulatory function and verifies the practicability using data of the well-studied yeast S.cereviseae. The novel insights offer extensive capabilities towards a better understanding of the combinatorial control driving transcriptional regulation. Contents Protein Complex Prediction Protein-Protein Interaction Networks Domain-Domain Interaction Networks Combinatorial Algorithms Algorithm Engineering Target Groups Computational biologists and biologists working with gene regulatory networks Computer scientists interested in biological issues The Author Currently, the author is pursuing his Ph.D. at the Center for Bioinformatics in Saarbrucken, Germany.
    電子資源: http://dx.doi.org/10.1007/978-3-658-08269-7
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