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The MIF handbook[electronic resource] /

Bucala, Richard.

The MIF handbook[electronic resource] /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
杜威分類號:	572/.696
書名/作者:	The MIF handbook/ edited by Richard Bucala.
其他作者:	Bucala, Richard.
出版者:	Singapore ; : World Scientific,, c2012.
面頁冊數:	1 online resource (viii, 390 p.) : : ill.
標題:	Cytokines.
標題:	Immune response - Regulation.
ISBN:	9789814335362 (electronic bk.)
ISBN:	9814335363 (electronic bk.)
ISBN:	128359367X
ISBN:	9781283593670
書目註:	Includes bibliographical references and index.
摘要、提要註:	The role of the cytokine, macrophage migration inhibitory factor (MIF), in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well established. The aim of this handbook is to provide an authoritative volume covering all aspects of MIF, from basic molecular biology to structure-function relationships, pathophysiology, genetics, and drug development. Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, cardiac physiology, and neurodevelopment. MIF's molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. Unique structural features of the protein, such as an intrinsic catalytic activity, and the continuing elucidation of its receptor-dependent mechanism of action offer attractive opportunities for therapeutic intervention. This volume will provide a comprehensive synthesis of the state of the art of MIF science.
電子資源:	http://www.worldscientific.com/worldscibooks/10.1142/8032#t=toc

The MIF handbook[electronic resource] /
The MIF handbook[electronic resource] /edited by Richard Bucala. - Singapore ;World Scientific,c2012. - 1 online resource (viii, 390 p.) :ill.

Includes bibliographical references and index.

The role of the cytokine, macrophage migration inhibitory factor (MIF), in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well established. The aim of this handbook is to provide an authoritative volume covering all aspects of MIF, from basic molecular biology to structure-function relationships, pathophysiology, genetics, and drug development. Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, cardiac physiology, and neurodevelopment. MIF's molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. Unique structural features of the protein, such as an intrinsic catalytic activity, and the continuing elucidation of its receptor-dependent mechanism of action offer attractive opportunities for therapeutic intervention. This volume will provide a comprehensive synthesis of the state of the art of MIF science.

ISBN: 9789814335362 (electronic bk.)Subjects--Topical Terms:

428409
Cytokines.
Index Terms--Genre/Form:

336502
Electronic books.

LC Class. No.: QP552.M54 / .M54 2012eb

Dewey Class. No.: 572/.696

The MIF handbook[electronic resource] /
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005 20140116093411.0
006 m o d
007 cr cnu---unuuu
008 140207s2012 si a ob 001 0 eng d
020 $a 9789814335362 (electronic bk.)
020 $a 9814335363 (electronic bk.)
020 $z 9789814335355
020 $z 9814335355
020 $a 128359367X
020 $a 9781283593670
035 $a ocn810933230
040 $a N $c N $d IDEBK $d OCLCQ $d CDX
050 4 $a QP552.M54 $b .M54 2012eb
082 0 4 $a 572/.696 $2 23
245 0 4 $a The MIF handbook $h [electronic resource] / $c edited by Richard Bucala.
260 $a Singapore ; $a Hackensack, NJ. : $b World Scientific, $c c2012.
300 $a 1 online resource (viii, 390 p.) : $b ill.
504 $a Includes bibliographical references and index.
520 $a The role of the cytokine, macrophage migration inhibitory factor (MIF), in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well established. The aim of this handbook is to provide an authoritative volume covering all aspects of MIF, from basic molecular biology to structure-function relationships, pathophysiology, genetics, and drug development. Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, cardiac physiology, and neurodevelopment. MIF's molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. Unique structural features of the protein, such as an intrinsic catalytic activity, and the continuing elucidation of its receptor-dependent mechanism of action offer attractive opportunities for therapeutic intervention. This volume will provide a comprehensive synthesis of the state of the art of MIF science.
588 $a Description based on print version record.
650 0 $a Cytokines. $3 428409
650 0 $a Immune response $x Regulation. $3 428276
655 4 $a Electronic books. $2 local $3 336502
700 1 $a Bucala, Richard. $3 490092
856 4 0 $u http://www.worldscientific.com/worldscibooks/10.1142/8032#t=toc

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