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Fluorine in pharmaceutical and medicinal chemistry[electronic resource] :from biophysical aspects to clinial applications /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
杜威分類號:	615.19
書名/作者:	Fluorine in pharmaceutical and medicinal chemistry : from biophysical aspects to clinial applications // Véronique Gouverneur, Klaus Müller, editors.
其他作者:	Gouverneur, Véronique.
出版者:	London : : Imperial College Press ;, 2012.
面頁冊數:	1 online resource (xxiii, 546 p.) : : ill. (some col.)
標題:	Fluorine.
標題:	Pharmaceutical chemistry.
ISBN:	9781848166363 (electronic bk.)
ISBN:	1848166362 (electronic bk.)
書目註:	Includes bibliographical references and index.
摘要、提要註:	Fluorine chemistry is an expanding area of research that is attracting international interest, due to the impact of fluorine in drug discovery and in clinical and molecular imaging (e.g. PET, MRI). Many researchers and academics are entering this area of research, while scientists in industrial and clinical environments are also indirectly exposed to fluorine chemistry through the use of fluorinated compounds for imaging. This book provides an overview of the impact that fluorine has made in the life sciences. In the first section, the emphasis is on how fluorine substitution of amino acids, peptides, nucleobases and carbohydrates can provide invaluable information at a molecular level. The following chapters provide answers to the key questions posed on the importance of fluorine in drug discovery and clinical applications. For example, the reader will discover how fluorine has found its place as a key element in improving drug efficacy, with reference to some of the best-selling drugs on the market. Finally, a thorough review on the design, synthesis and use of 18F-radiotracers for positron emission tomography is provided, and this is complemented with a discussion on how 19F NMR has advanced molecular and clinical imaging.
電子資源:	http://www.worldscientific.com/worldscibooks/10.1142/P746#t=toc

Fluorine in pharmaceutical and medicinal chemistry[electronic resource] :from biophysical aspects to clinial applications /
Fluorine in pharmaceutical and medicinal chemistryfrom biophysical aspects to clinial applications /[electronic resource] :Véronique Gouverneur, Klaus Müller, editors. - London :Imperial College Press ;2012. - 1 online resource (xxiii, 546 p.) :ill. (some col.) - Molecular medicine and medicinal chemistry ;6. - Molecular medicine and medicinal chemistry ;v. 1..

Includes bibliographical references and index.

Fluorine chemistry is an expanding area of research that is attracting international interest, due to the impact of fluorine in drug discovery and in clinical and molecular imaging (e.g. PET, MRI). Many researchers and academics are entering this area of research, while scientists in industrial and clinical environments are also indirectly exposed to fluorine chemistry through the use of fluorinated compounds for imaging. This book provides an overview of the impact that fluorine has made in the life sciences. In the first section, the emphasis is on how fluorine substitution of amino acids, peptides, nucleobases and carbohydrates can provide invaluable information at a molecular level. The following chapters provide answers to the key questions posed on the importance of fluorine in drug discovery and clinical applications. For example, the reader will discover how fluorine has found its place as a key element in improving drug efficacy, with reference to some of the best-selling drugs on the market. Finally, a thorough review on the design, synthesis and use of 18F-radiotracers for positron emission tomography is provided, and this is complemented with a discussion on how 19F NMR has advanced molecular and clinical imaging.

ISBN: 9781848166363 (electronic bk.)

Standard No.: 9786613645890Subjects--Topical Terms:

556652
Fluorine.
Index Terms--Genre/Form:

336502
Electronic books.

LC Class. No.: RS400 / .F58 2012eb

Dewey Class. No.: 615.19

National Library of Medicine Call No.: QV 185 / F58 2012

Fluorine in pharmaceutical and medicinal chemistry[electronic resource] :from biophysical aspects to clinial applications /
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588 $a Description based on print version record.
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