大葉大學圖書館 |

Proteases of infectious agents[electronic resource] /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
杜威分類號:	572/.76
書名/作者:	Proteases of infectious agents/ edited by Ben M. Dunn.
其他作者:	Dunn, Ben M.
出版者:	San Diego, Calif. : : Academic,, c1999.
面頁冊數:	1 online resource (xvii, 282 p., [15] p. of col. plates) : : ill. (some col.)
標題:	Proteolytic enzymes.
標題:	Protease inhibitors.
標題:	Microbial enzymes.
標題:	Protease Inhibitors - chemical synthesis.
標題:	Protease Inhibitors - therapeutic use.
標題:	Communicable Diseases - enzymology.
標題:	Communicable Diseases - therapy.
標題:	Communicable diseases.
標題:	Enzymes protéolytiques.
標題:	Antiprotéases.
標題:	Enzymes microbiennes.
ISBN:	9780124205109
ISBN:	0124205100
ISBN:	9786611025113
ISBN:	6611025111
內容註:	J. Erickson and M. Eissenstat, HIV Protease as a Target for the Design of Antiviral Agents for AIDS. -- C. Steinkühler, A. Urbani, and R. De Francesco, Proteases of the Hepatitis C Virus. -- S. Abdel-Meguid and X. Qiu, Human Herpesvirus Proteases. -- C. Abad-Zapatero, R. Goldman, and K. Stewart, The Secreted Proteinases from Candida: Challenges for Structure-Aided Drug Design. -- M.N.G. James and E. Bergman, Proteolytic Enzymes of the Viruses of the Family Picornaviridae. -- C. Berry, Proteases as Drug Targets in the Treatment of Malaria. -- J. Cazzulo, Chagas Disease. -- H. Kido, Y. Chen, M. Murakami, Y. Beppu, and T. Towatari, Cellular Proteinases and Viral Infection: Influenza Virus, Sendai Virus, and HIV-1. -- M. Lively, Bacterial Type 1 Signal Peptidases. -- J.A. Garcia, M.R. Fernández-Fernández, and J.J. López-Moya, Proteinases Involved in Plant Virus Genome Expression. -- Subject Index.
摘要、提要註:	Proteases are enzymes that essentially "eat" protein. Without proteases, infectious organisms cannot properly mount an attack against a host. It is for this reason that proteases have become popular targets for drug discovery. Research has shown that if you can inhibit the protease, you can defend against the invading microbe. The defense against HIV, the virus that causes AIDS, is the best-documented case of the efficacy of protease inhibitors. Researchers are now trying to deploy this strategy against several infectious agents. This book gives information that is useful in that search. Proteases of Infectious Agents collects reviews from leading experts describing the latest information on the properties of key enzymes from a variety of viruses, fungi, and parasites. Each chapter provides the critical facts needed to initiate a drug discovery effort in that particular area. Key Features * Includes information on the basic biology and function of proteases * Provides global survey of current research efforts in protease inhibitors * Illustrates how structure-based drug design targets effective and selective compounds * Highlights important diseases that provide economically important targets * Describes the role of proteases as important new targets for drug discovery.
電子資源:	http://www.sciencedirect.com/science/book/9780124205109

Proteases of infectious agents[electronic resource] /
Proteases of infectious agents[electronic resource] /edited by Ben M. Dunn. - San Diego, Calif. :Academic,c1999. - 1 online resource (xvii, 282 p., [15] p. of col. plates) :ill. (some col.)

J. Erickson and M. Eissenstat, HIV Protease as a Target for the Design of Antiviral Agents for AIDS. -- C. Steinkühler, A. Urbani, and R. De Francesco, Proteases of the Hepatitis C Virus. -- S. Abdel-Meguid and X. Qiu, Human Herpesvirus Proteases. -- C. Abad-Zapatero, R. Goldman, and K. Stewart, The Secreted Proteinases from Candida: Challenges for Structure-Aided Drug Design. -- M.N.G. James and E. Bergman, Proteolytic Enzymes of the Viruses of the Family Picornaviridae. -- C. Berry, Proteases as Drug Targets in the Treatment of Malaria. -- J. Cazzulo, Chagas Disease. -- H. Kido, Y. Chen, M. Murakami, Y. Beppu, and T. Towatari, Cellular Proteinases and Viral Infection: Influenza Virus, Sendai Virus, and HIV-1. -- M. Lively, Bacterial Type 1 Signal Peptidases. -- J.A. Garcia, M.R. Fernández-Fernández, and J.J. López-Moya, Proteinases Involved in Plant Virus Genome Expression. -- Subject Index.

Proteases are enzymes that essentially "eat" protein. Without proteases, infectious organisms cannot properly mount an attack against a host. It is for this reason that proteases have become popular targets for drug discovery. Research has shown that if you can inhibit the protease, you can defend against the invading microbe. The defense against HIV, the virus that causes AIDS, is the best-documented case of the efficacy of protease inhibitors. Researchers are now trying to deploy this strategy against several infectious agents. This book gives information that is useful in that search. Proteases of Infectious Agents collects reviews from leading experts describing the latest information on the properties of key enzymes from a variety of viruses, fungi, and parasites. Each chapter provides the critical facts needed to initiate a drug discovery effort in that particular area. Key Features * Includes information on the basic biology and function of proteases * Provides global survey of current research efforts in protease inhibitors * Illustrates how structure-based drug design targets effective and selective compounds * Highlights important diseases that provide economically important targets * Describes the role of proteases as important new targets for drug discovery.

ISBN: 9780124205109

Source: 79195:79195Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

493942
Proteolytic enzymes.
Index Terms--Genre/Form:

336502
Electronic books.

LC Class. No.: QP609.P78 / P746 1999eb

Dewey Class. No.: 572/.76

National Agricultural Library Call No.: RC112 / .P76 1999

National Library of Medicine Call No.: 1999 F-117

Proteases of infectious agents[electronic resource] /
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300 $a 1 online resource (xvii, 282 p., [15] p. of col. plates) : $b ill. (some col.)
505 0 $a J. Erickson and M. Eissenstat, HIV Protease as a Target for the Design of Antiviral Agents for AIDS. -- C. Steinkühler, A. Urbani, and R. De Francesco, Proteases of the Hepatitis C Virus. -- S. Abdel-Meguid and X. Qiu, Human Herpesvirus Proteases. -- C. Abad-Zapatero, R. Goldman, and K. Stewart, The Secreted Proteinases from Candida: Challenges for Structure-Aided Drug Design. -- M.N.G. James and E. Bergman, Proteolytic Enzymes of the Viruses of the Family Picornaviridae. -- C. Berry, Proteases as Drug Targets in the Treatment of Malaria. -- J. Cazzulo, Chagas Disease. -- H. Kido, Y. Chen, M. Murakami, Y. Beppu, and T. Towatari, Cellular Proteinases and Viral Infection: Influenza Virus, Sendai Virus, and HIV-1. -- M. Lively, Bacterial Type 1 Signal Peptidases. -- J.A. Garcia, M.R. Fernández-Fernández, and J.J. López-Moya, Proteinases Involved in Plant Virus Genome Expression. -- Subject Index.
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520 $a Proteases are enzymes that essentially "eat" protein. Without proteases, infectious organisms cannot properly mount an attack against a host. It is for this reason that proteases have become popular targets for drug discovery. Research has shown that if you can inhibit the protease, you can defend against the invading microbe. The defense against HIV, the virus that causes AIDS, is the best-documented case of the efficacy of protease inhibitors. Researchers are now trying to deploy this strategy against several infectious agents. This book gives information that is useful in that search. Proteases of Infectious Agents collects reviews from leading experts describing the latest information on the properties of key enzymes from a variety of viruses, fungi, and parasites. Each chapter provides the critical facts needed to initiate a drug discovery effort in that particular area. Key Features * Includes information on the basic biology and function of proteases * Provides global survey of current research efforts in protease inhibitors * Illustrates how structure-based drug design targets effective and selective compounds * Highlights important diseases that provide economically important targets * Describes the role of proteases as important new targets for drug discovery.
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650 2 2 $a Communicable Diseases $x enzymology. $3 493947
650 2 2 $a Communicable Diseases $x therapy. $3 340358
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650 6 $a Enzymes protéolytiques. $3 493948
650 6 $a Antiprotéases. $3 493949
650 6 $a Enzymes microbiennes. $3 493950
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700 1 $a Dunn, Ben M. $3 493941
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