• Gene therapy of cancer[electronic resource] :translational approaches from preclinical studies to clinical implementation /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 616.99/4042
    書名/作者: Gene therapy of cancer : translational approaches from preclinical studies to clinical implementation // edited by Edmund C. Lattime, Stanton L. Gerson.
    其他作者: Lattime, Edmund C.,
    出版者: San Diego, CA : : Academic Press,, c2002.
    面頁冊數: 1 online resource (xix, 534 p.) : : ill. (some col.)
    標題: Cancer - Gene therapy.
    標題: Cancer - Immunotherapy.
    標題: Neoplasms - genetics.
    標題: Neoplasms - therapy.
    標題: Gene Therapy - methods.
    標題: Immunotherapy - methods.
    標題: Protein Biosynthesis.
    標題: Cancer - Thérapie génique.
    標題: Cancer - Immunothérapie.
    標題: MEDICAL - Oncology.
    標題: HEALTH & FITNESS - Diseases
    ISBN: 9780124375512
    ISBN: 0124375510
    ISBN: 9780080491363 (electronic bk.)
    ISBN: 0080491367 (electronic bk.)
    書目註: Includes bibliographical references and index.
    內容註: Ch. 1. Retroviral vector design for cancer gene therapy -- Ch. 2. Noninfectious gene transfer and expression systems for cancer gene therapy -- Ch. 3. Parvovirus vectors for the gene therapy of cancer -- Ch. 4. Antibody-targeted gene therapy -- Ch. 5. Ribozymes in cancer gene therapy -- Ch. 6. The advent of lentiviral vectors: prospects for cancer therapy -- Ch. 7. Immunologic targets for the gene therapy of cancer -- Ch. 8. Development of epitope-specific immunotherapies for human malignancies and premalignant lesions expressing mutated ras genes -- Ch. 9. Introduction to dendritic cells -- Ch. 10. DNA and dendritic cell-based genetic immunization against cancer -- Ch. 11. RNA-transfected dendritic cells as immunogens -- Ch. 12. In Situ immune modulation using recombinant vaccinia virus vectors: preclinical studies to clinical implementation -- Ch. 13. The use of particle-mediated gene transfer for immunotherapy of cancer -- Ch. 14. Applications of gene transfer in the adoptive immunotherapy of cancer -- Ch. 15. Update on the use of genetically modified hematopoietic stem cells for cancer therapy -- Ch. 16. Clinical applications of tumor-suppressor gene therapy -- Ch. 17. Cancer gene therapy with tumor suppressor genes involved in cell-cycle control.
    摘要、提要註: The Second Edition of Gene Therapy of Cancer provides crucial updates on the basic science and ongoing research in this field, examining the state of the art technology in gene therapy and its therapeutic applications to the treatment of cancer. The clinical chapters are improved to include new areas of research and more successful trials. Chapters emphasize the scientific basis of gene therapy using immune, oncogene, antisense, pro-drug activating, and drug resistance gene targets, while other chapters discuss therapeutic approaches and clinical applications. This book is a valuable reference for anyone needing to stay abreast of the latest advances in gene therapy treatment for cancer. Key Features * Provides in-depth description of targeted systems and treatment strategies * Explains the underlying cancer biology necessary for understanding a given therapeutic approach * Extensively covers immune therapeutics of vaccines, cytokines, and peptide-induced responses * Presents translational focus with emphasis on requirements for clinical implementation * Incorporates detailed illustrations of vectors and therapeutic approaches ideal for classroom presentations and general reference.
    電子資源: http://www.sciencedirect.com/science/book/9780124375512
評論
Export
取書館別
 
 
變更密碼
登入