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Bisphosphonates in bone disease[electronic resource] :from the laboratory to the patient /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
杜威分類號:	616.71061
書名/作者:	Bisphosphonates in bone disease : from the laboratory to the patient // Herbert Fleisch.
作者:	Fleisch, Herbert.
出版者:	San Diego : : Academic Press,, c2000.
面頁冊數:	1 online resource (xii, 212 p.) : : ill.
標題:	Diphosphonates - Therapeutic use.
標題:	Bones - Diseases
標題:	Bone Diseases - drug therapy.
標題:	Bone Diseases - metabolism.
標題:	Diphosphonates - pharmacology.
標題:	Diphosphonates - therapeutic use.
標題:	MEDICAL - Orthopedics.
標題:	HEALTH & FITNESS - Diseases
標題:	MEDICAL - Rheumatology.
標題:	Diphosphonate.
標題:	Knochenkrankheit.
ISBN:	9780122603716
ISBN:	0122603710
ISBN:	9780080528113 (electronic bk.)
ISBN:	0080528112 (electronic bk.)
ISBN:	9780080573908 (electronic bk.)
ISBN:	0080573908 (electronic bk.)
書目註:	Includes bibliographical references and index.
內容註:	Bone and Mineral Metabolism: -- Bone Physiology: -- Morphology. -- Composition of bone. -- Modeling and remodeling. -- Calcium homeostasis. -- Bone as an organ. -- Assessment of bone turnover. -- Bisphosphonates-Preclinical: -- Background to the pharmacological development: -- Chemistry. -- Actions. -- Physicochemical effects. -- Biological effects. -- Inhibition of bone resorption. -- Inhibition of mineralization. -- Pharmocokinetics: -- Intestinal absorption. -- Distribution. -- Renal clearance. -- Other modes of application. -- Animal toxicology: -- Acute toxicology. -- Nonacute toxicology. -- Bisphosphonates-clinical: -- Introduction. -- Paget's Disease: -- Definition. -- Epidemiology. -- Pathophysiology. -- Clinical manifestations. -- Treatment with drugs other than bisphosphonates. -- Treatment with bisphosphonates. -- Osteolytic tumor-induced bone disease: -- Definition. -- Pathophysiology. -- Clinical manifestations. -- Treatment with drugs other than bisphosphonates. -- Treatment with bisphosphonates. -- Non-tumor induced hypercalcemia: -- Definition. -- Pathophysiology. -- Clinical manifestations. -- Treatment with drugs other than bisphosphonates. -- Treatment with bisphosphonates. -- Osteoporosis: -- Definition. -- Epidemiology. -- Pathophysiology. -- Clinical manifestations. -- Treatment with drugs other than bisphosphonates. -- Treatment with bisphosphonates. -- Heterotopic calcification and ossification: -- Definition. -- Pathophysiology. -- Clinical manifestations. -- Treatment with drugs other than bisphosphonates. -- Treatment with bisphosphonates. -- Other diseases: -- Adverse events: -- Bisphosphonates in general. -- Individual bisphosphonates. -- Contraindications. -- Future prospects. -- Commercially available bisphosphonates: -- Index.
摘要、提要註:	This book is an essential handbook on bisphosphonates, the most widely used new class of drugs for osteoporosis therapy. It reviews basic physiology in addition to the indications and adverse reactions of these drugs. Bisphosphonates in Bone Disease, 4E, discusses the compounds' chemistry, mechanisms of action, and animal toxicology before presenting a clinical picture of the diseases treated by bisphosphonates. The book provides a table listing the trade names of the commercially available bisphosphonates, registered indications, and the available forms for various countries. The revised Fourth Edition contains approximately 50% new material, including information on all of the latest drugs. * The revised fourth edition contains approximately 50% new material * Includes information on all the latest drugs.
電子資源:	http://www.sciencedirect.com/science/book/9780122603716

Bisphosphonates in bone disease[electronic resource] :from the laboratory to the patient /
Fleisch, Herbert.

Bisphosphonates in bone diseasefrom the laboratory to the patient /[electronic resource] :Herbert Fleisch. - 4th ed. - San Diego :Academic Press,c2000. - 1 online resource (xii, 212 p.) :ill.

Includes bibliographical references and index.

Bone and Mineral Metabolism: -- Bone Physiology: -- Morphology. -- Composition of bone. -- Modeling and remodeling. -- Calcium homeostasis. -- Bone as an organ. -- Assessment of bone turnover. -- Bisphosphonates-Preclinical: -- Background to the pharmacological development: -- Chemistry. -- Actions. -- Physicochemical effects. -- Biological effects. -- Inhibition of bone resorption. -- Inhibition of mineralization. -- Pharmocokinetics: -- Intestinal absorption. -- Distribution. -- Renal clearance. -- Other modes of application. -- Animal toxicology: -- Acute toxicology. -- Nonacute toxicology. -- Bisphosphonates-clinical: -- Introduction. -- Paget's Disease: -- Definition. -- Epidemiology. -- Pathophysiology. -- Clinical manifestations. -- Treatment with drugs other than bisphosphonates. -- Treatment with bisphosphonates. -- Osteolytic tumor-induced bone disease: -- Definition. -- Pathophysiology. -- Clinical manifestations. -- Treatment with drugs other than bisphosphonates. -- Treatment with bisphosphonates. -- Non-tumor induced hypercalcemia: -- Definition. -- Pathophysiology. -- Clinical manifestations. -- Treatment with drugs other than bisphosphonates. -- Treatment with bisphosphonates. -- Osteoporosis: -- Definition. -- Epidemiology. -- Pathophysiology. -- Clinical manifestations. -- Treatment with drugs other than bisphosphonates. -- Treatment with bisphosphonates. -- Heterotopic calcification and ossification: -- Definition. -- Pathophysiology. -- Clinical manifestations. -- Treatment with drugs other than bisphosphonates. -- Treatment with bisphosphonates. -- Other diseases: -- Adverse events: -- Bisphosphonates in general. -- Individual bisphosphonates. -- Contraindications. -- Future prospects. -- Commercially available bisphosphonates: -- Index.

This book is an essential handbook on bisphosphonates, the most widely used new class of drugs for osteoporosis therapy. It reviews basic physiology in addition to the indications and adverse reactions of these drugs. Bisphosphonates in Bone Disease, 4E, discusses the compounds' chemistry, mechanisms of action, and animal toxicology before presenting a clinical picture of the diseases treated by bisphosphonates. The book provides a table listing the trade names of the commercially available bisphosphonates, registered indications, and the available forms for various countries. The revised Fourth Edition contains approximately 50% new material, including information on all of the latest drugs. * The revised fourth edition contains approximately 50% new material * Includes information on all the latest drugs.

ISBN: 9780122603716

Source: 89503:89503Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

493157
Diphosphonates
--Therapeutic use.Index Terms--Genre/Form:

336502
Electronic books.

LC Class. No.: RC930 / .F54 2000eb

Dewey Class. No.: 616.71061

National Library of Medicine Call No.: 2000 E-781

Bisphosphonates in bone disease[electronic resource] :from the laboratory to the patient /
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