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Therapeutic applications of quadrupl...
~
Neidle, Stephen.
Therapeutic applications of quadruplex nucleic acids /
紀錄類型:
書目-語言資料,印刷品 : Monograph/item
杜威分類號:
615.36
書名/作者:
Therapeutic applications of quadruplex nucleic acids // Stephen Neidle.
作者:
Neidle, Stephen.
出版者:
London ; : Elsevier/Academic Press,, 2012.
面頁冊數:
xii, 196 p. : : ill. ;; 24 cm.
標題:
Quadruplex nucleic acids - Therapeutic use.
ISBN:
9780123751386 (hbk.) :
ISBN:
0123751381 (hbk.)
書目註:
Includes bibliographical references and index.
內容註:
Introduction: quadruplexes and their biology -- DNA and RNA quadruplex structures -- The structures of human telomeric DNA quadruplexes -- Telomeric quadruplex ligands I: anthraquinones and acridines -- Telomeric quadruplex ligands II: polycyclic and non-fused ring compounds -- The biology and pharmacology of telomeric quadruplex ligands -- Genomic quadruplexes as therapeutic targets -- RNA quadruplexes -- Design principles for quadruplex-binding small molecules -- The determination of quadruplex structures.
摘要、提要註:
"Therapeutic applications of quadruplex nucleic acids provides a single comprehensive survey that describes and assesses recent advances in quadruplex therapeutics and targeting strategies. It also covers the underlying fundamentals of such topics as quadruplex structure, small-molecule recognition, biological roles of genomic quadruplexes, and quadruplex informatics"--P. [4] of cover.
Therapeutic applications of quadruplex nucleic acids /
Neidle, Stephen.
Therapeutic applications of quadruplex nucleic acids /
Stephen Neidle. - 1st ed. - London ;Elsevier/Academic Press,2012. - xii, 196 p. :ill. ;24 cm.
Includes bibliographical references and index.
Introduction: quadruplexes and their biology -- DNA and RNA quadruplex structures -- The structures of human telomeric DNA quadruplexes -- Telomeric quadruplex ligands I: anthraquinones and acridines -- Telomeric quadruplex ligands II: polycyclic and non-fused ring compounds -- The biology and pharmacology of telomeric quadruplex ligands -- Genomic quadruplexes as therapeutic targets -- RNA quadruplexes -- Design principles for quadruplex-binding small molecules -- The determination of quadruplex structures.
"Therapeutic applications of quadruplex nucleic acids provides a single comprehensive survey that describes and assesses recent advances in quadruplex therapeutics and targeting strategies. It also covers the underlying fundamentals of such topics as quadruplex structure, small-molecule recognition, biological roles of genomic quadruplexes, and quadruplex informatics"--P. [4] of cover.
ISBN: 9780123751386 (hbk.) :NTD 3,811
LCCN: 2011293620
Nat. Bib. No.: GBB198738bnb
Nat. Bib. Agency Control No.: 015873824UkSubjects--Topical Terms:
456003
Quadruplex nucleic acids
--Therapeutic use.
LC Class. No.: RM666.N87 / N45 2012
Dewey Class. No.: 615.36
Therapeutic applications of quadruplex nucleic acids /
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