大葉大學圖書館 |

Adenoviral vectors for gene therapy[electronic resource] /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
杜威分類號:	616/.042
書名/作者:	Adenoviral vectors for gene therapy/ edited by David T. Curiel, Joanne T. Douglas.
其他作者:	Douglas, Joanne T.
出版者:	Amsterdam ; : Academic Press,, c2002.
面頁冊數:	1 online resource (xxviii, 677 p.) : : ill.
標題:	Gene therapy.
標題:	Adenoviruses.
標題:	Gene Therapy - methods.
標題:	Adenoviridae.
標題:	Genetic Vectors - therapeutic use.
標題:	Th�erapie g�enique.
標題:	Ad�enovirus.
標題:	HEALTH & FITNESS - Diseases
標題:	MEDICAL - Genetics.
標題:	Adenov�irus.
標題:	Genes virais.
標題:	V�irus de dna.
ISBN:	9780121995041
ISBN:	0121995046
ISBN:	9781435632004 (electronic bk.)
ISBN:	1435632001 (electronic bk.)
書目註:	Includes bibliographical references.
內容註:	Adenovirus Structure -- Biology of Adenovirus Cell Entry -- Adenovirus Replication -- Adenoviral Vector Construction I: Mammalian Systems -- Adenoviral Vector Construction II: Bacterial Systems -- Propagation of Adenoviral Vectors: Use of PER. C6 Cells -- Purification of Adenovirus -- Targeted Adenoviral Vectors I: Transductional Targeting -- Targeted Adenoviral Vectors II: Transcriptional Targeting -- Development of Attenuated Replication Competent Adenoviruses ARCAs) for the treatment of Prostate Cancer -- Replication-Selective Oncolytic Adenovirus EI-Region Mutants: Virotherapy for Cancer -- Innate Immune Responses to in Vivo Adenovirus Infection -- Humoral Immune Response -- Novel Methods to Eliminate the Immune Response to Adenovirus Gene Therapy -- High-Capacity "Gutless" Adenoviral Vectors: Technical Aspects and Applications -- Xenogenic Adenoviral Vectors -- Hybrid Adenoviral Vectors -- Utility of Adenoviral Vectors in Animal Models of Human Disease I: Cancer -- Utiltity of Adenoviral Vectors in Animal Models of Human Disease II: Genetic Disease -- Utility of Adenoviral Vectors in Animal Models of Human Disease III: Acquired Diseases -- Testing of Adenoviral Vector Gene Transfer Products: FDA Expectations -- Imaging Adenovirus-Medicated Gene Transfer.
摘要、提要註:	Adenoviral Vectors for Gene Therapy provides detailed and comprehensive coverage of these important therapeutic agents. The topics covered in this book range from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology and the use of adenoviral vectors in preclinical animal models, to regulatory issues which must be considered prior to the initiation of human clinical gene therapy trials. The broad scope of this unique volume provides the reader with a complete understanding of the development and use of adenoviral vectors. Key Features * Provides complete coverage of basic biology of adenoviruses, as well as the construction, propagation and purification of adenoviral vectors * Introduces common strategies for the development of adenoviral vectors along with cutting-edge methods for their improvement * Demonstrates noninvasive imaging of adenovirus-mediated gene transfer * Discusses utility of adenoviral vectors in animal disease models * Considers Federal Drug Administration regulations for human clinical trials.
電子資源:	http://www.sciencedirect.com/science/book/9780121995041

Adenoviral vectors for gene therapy[electronic resource] /
Adenoviral vectors for gene therapy[electronic resource] /edited by David T. Curiel, Joanne T. Douglas. - Amsterdam ;Academic Press,c2002. - 1 online resource (xxviii, 677 p.) :ill.

Includes bibliographical references.

Adenovirus Structure -- Biology of Adenovirus Cell Entry -- Adenovirus Replication -- Adenoviral Vector Construction I: Mammalian Systems -- Adenoviral Vector Construction II: Bacterial Systems -- Propagation of Adenoviral Vectors: Use of PER. C6 Cells -- Purification of Adenovirus -- Targeted Adenoviral Vectors I: Transductional Targeting -- Targeted Adenoviral Vectors II: Transcriptional Targeting -- Development of Attenuated Replication Competent Adenoviruses ARCAs) for the treatment of Prostate Cancer -- Replication-Selective Oncolytic Adenovirus EI-Region Mutants: Virotherapy for Cancer -- Innate Immune Responses to in Vivo Adenovirus Infection -- Humoral Immune Response -- Novel Methods to Eliminate the Immune Response to Adenovirus Gene Therapy -- High-Capacity "Gutless" Adenoviral Vectors: Technical Aspects and Applications -- Xenogenic Adenoviral Vectors -- Hybrid Adenoviral Vectors -- Utility of Adenoviral Vectors in Animal Models of Human Disease I: Cancer -- Utiltity of Adenoviral Vectors in Animal Models of Human Disease II: Genetic Disease -- Utility of Adenoviral Vectors in Animal Models of Human Disease III: Acquired Diseases -- Testing of Adenoviral Vector Gene Transfer Products: FDA Expectations -- Imaging Adenovirus-Medicated Gene Transfer.

Adenoviral Vectors for Gene Therapy provides detailed and comprehensive coverage of these important therapeutic agents. The topics covered in this book range from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology and the use of adenoviral vectors in preclinical animal models, to regulatory issues which must be considered prior to the initiation of human clinical gene therapy trials. The broad scope of this unique volume provides the reader with a complete understanding of the development and use of adenoviral vectors. Key Features * Provides complete coverage of basic biology of adenoviruses, as well as the construction, propagation and purification of adenoviral vectors * Introduces common strategies for the development of adenoviral vectors along with cutting-edge methods for their improvement * Demonstrates noninvasive imaging of adenovirus-mediated gene transfer * Discusses utility of adenoviral vectors in animal disease models * Considers Federal Drug Administration regulations for human clinical trials.

ISBN: 9780121995041

Source: 89480:89480Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

427973
Gene therapy.
Index Terms--Genre/Form:

336502
Electronic books.

LC Class. No.: RB155.8 / .A34 2002eb

Dewey Class. No.: 616/.042

National Library of Medicine Call No.: 2002 H-966

Adenoviral vectors for gene therapy[electronic resource] /
LDR:04007cam 2200433Ia 4500 001 352657
003 OCoLC
005 20111122085744.0
006 m d
007 cr cn|||||||||
008 120110s2002 ne a ob 000 0 eng d
019 $a 209861927 $a 648350089
020 $a 9780121995041
020 $a 0121995046
020 $a 9781435632004 (electronic bk.)
020 $a 1435632001 (electronic bk.)
029 1 $a NZ1 $b 12432581
035 $a (OCoLC)162129420 $z (OCoLC)209861927 $z (OCoLC)648350089
035 $a ocn162129420
037 $a 89480:89480 $b Elsevier Science & Technology $n http://www.sciencedirect.com
040 $a OPELS $b eng $c OPELS $d OCLCQ $d N$T $d YDXCP $d E7B $d OCLCQ
049 $a TEFA
050 4 $a RB155.8 $b .A34 2002eb
060 4 $a 2002 H-966
060 4 $a QZ 50 $b A2326 2002
072 7 $a HEA $x 039060 $2 bisacsh
072 7 $a MED $x 107000 $2 bisacsh
082 0 4 $a 616/.042 $2 22
245 0 0 $a Adenoviral vectors for gene therapy $h [electronic resource] / $c edited by David T. Curiel, Joanne T. Douglas.
260 $a Amsterdam ; $a Boston : $b Academic Press, $c c2002.
300 $a 1 online resource (xxviii, 677 p.) : $b ill.
504 $a Includes bibliographical references.
505 0 $a Adenovirus Structure -- Biology of Adenovirus Cell Entry -- Adenovirus Replication -- Adenoviral Vector Construction I: Mammalian Systems -- Adenoviral Vector Construction II: Bacterial Systems -- Propagation of Adenoviral Vectors: Use of PER. C6 Cells -- Purification of Adenovirus -- Targeted Adenoviral Vectors I: Transductional Targeting -- Targeted Adenoviral Vectors II: Transcriptional Targeting -- Development of Attenuated Replication Competent Adenoviruses ARCAs) for the treatment of Prostate Cancer -- Replication-Selective Oncolytic Adenovirus EI-Region Mutants: Virotherapy for Cancer -- Innate Immune Responses to in Vivo Adenovirus Infection -- Humoral Immune Response -- Novel Methods to Eliminate the Immune Response to Adenovirus Gene Therapy -- High-Capacity "Gutless" Adenoviral Vectors: Technical Aspects and Applications -- Xenogenic Adenoviral Vectors -- Hybrid Adenoviral Vectors -- Utility of Adenoviral Vectors in Animal Models of Human Disease I: Cancer -- Utiltity of Adenoviral Vectors in Animal Models of Human Disease II: Genetic Disease -- Utility of Adenoviral Vectors in Animal Models of Human Disease III: Acquired Diseases -- Testing of Adenoviral Vector Gene Transfer Products: FDA Expectations -- Imaging Adenovirus-Medicated Gene Transfer.
520 $a Adenoviral Vectors for Gene Therapy provides detailed and comprehensive coverage of these important therapeutic agents. The topics covered in this book range from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology and the use of adenoviral vectors in preclinical animal models, to regulatory issues which must be considered prior to the initiation of human clinical gene therapy trials. The broad scope of this unique volume provides the reader with a complete understanding of the development and use of adenoviral vectors. Key Features * Provides complete coverage of basic biology of adenoviruses, as well as the construction, propagation and purification of adenoviral vectors * Introduces common strategies for the development of adenoviral vectors along with cutting-edge methods for their improvement * Demonstrates noninvasive imaging of adenovirus-mediated gene transfer * Discusses utility of adenoviral vectors in animal disease models * Considers Federal Drug Administration regulations for human clinical trials.
588 $a Description based on print version record.
650 0 $a Gene therapy. $3 427973
650 0 $a Adenoviruses. $3 443061
650 1 2 $a Gene Therapy $x methods. $3 438540
650 2 2 $a Adenoviridae. $3 443062
650 2 2 $a Genetic Vectors $x therapeutic use. $3 443063
650 6 $a Th�erapie g�enique. $3 443064
650 6 $a Ad�enovirus. $3 443065
650 7 $a HEALTH & FITNESS $x Diseases $x Genetic. $2 bisacsh $3 428430
650 7 $a MEDICAL $x Genetics. $2 bisacsh $3 428431
650 7 $a Adenov�irus. $2 larpcal $3 443066
650 7 $a Genes virais. $2 larpcal $3 443067
650 7 $a V�irus de dna. $2 larpcal $3 443068
655 4 $a Electronic books. $2 local $3 336502
700 1 $a Douglas, Joanne T. $3 443060
700 1 $a Curiel, David. $3 443059
776 0 8 $i Print version: $t Adenoviral vectors for gene therapy. $d Amsterdam ; Boston : Academic Press, c2002 $z 0121995046 $z 9780121995041 $w (DLC) 2001098272 $w (OCoLC)49780706
856 4 0 $3 ScienceDirect $u http://www.sciencedirect.com/science/book/9780121995041
938 $a YBP Library Services $b YANK $n 2783945
938 $a ebrary $b EBRY $n ebr10216805
994 $a C0 $b TEF