Microbial pathogenomics[electronic r...
Bereswill, Stefan.

 

  • Microbial pathogenomics[electronic resource] /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 616.9/201
    書名/作者: Microbial pathogenomics/ volume editors, Hilde de Reuse, Stefan Bereswill.
    其他作者: Reuse, Hilde de.
    出版者: Basel : : S. Karger,, 2010
    面頁冊數: 1 online resource : : ill. (some col.)
    附註: A global view of key aspects and future trends
    標題: Bacterial genomes.
    標題: Pathogenic bacteria.
    標題: Bacteria - genetics.
    標題: Bacteria - pathogenicity.
    標題: Genome, Bacterial.
    ISBN: 9783805591935
    書目註: Includes bibliographical references and indexes.
    摘要、提要註: 'Microbial Pathogenomics' contains a unique collection of reviews demonstrating how genomics has revolutionized our understanding of virulence, host-adaptation strategies and the evolution of bacterial pathogens. Current technologies – computational tools and functional approaches to genome analysis – are carefully documented and clearly illustrated. These include visualization tools for genome comparison, databases, in silico metabolic reconstructions and function prediction as well as interactomics for the study of protein-protein interactions. The concepts of pan-genomics and reverse vaccinology are introduced as strategies when addressing the challenge presented by bacterial diversity in the prevention and treatment of infectious diseases. The authors explore individual bacterial pathogens and discuss the mechanisms that have contributed to their evolutionary success. Special cases of host adaptation, for example, are illustrated by Helicobacter pylori and 'Mycobacterium tuberculosis' which are human-specific and highly persistent; further bacteria discussed include 'Escherichia coli, Campylobacter, Pseudomonas, Legionella, Bartonella, Burkholderia' and 'Staphylococcus'.'Microbial Pathogenomics' provides the reader with a global view of key aspects and future trends in bacterial pathogenomics and evaluates their impact on the understanding and treatment of infectious diseases. Well illustrated and accessible to both specialists and nonspecialists, it is recommended not only for researchers in microbiology, genomics and biotechnology, but also for lecturers and teachers.
    電子資源: http://content.karger.com/ProdukteDB/produkte.asp?Aktion=showproducts&searchWhat=books&searchParm=toc&ProduktNr=250316
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