Advances in medicinal chemistry.[ele...
Dax, S. L.

 

  • Advances in medicinal chemistry.[electronic resource].Volume 5
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 615/.19
    書名/作者: Advances in medicinal chemistry.
    其他作者: Reitz, A. B.
    出版者: [S.l.] : : Elsevier Science,, 2000.
    面頁冊數: 1 v.
    標題: Pharmaceutical chemistry.
    ISBN: 9780762305933
    ISBN: 0762305932
    內容註: Preface. Immunophilins: the next generation. Discovery of ABT-594 and related neuronal nicotinic acetylcholine receptor modulators as analgesic agents: medicinal chemistry and biology. Discovery and preclinical evaluation of novel dopamine partial agonists as antipsychotic agents. Nonpeptide inhibitors of HIV protease.
    摘要、提要註: Volume 5 of Advances in Medicinal Chemistry contains four intriguing and detailed accounts of the close interface between synthetic chemistry, structure-activity relationships, biochemistry, and pharmacology. In Chapter 1, there is a comprehensive survey of the immunophilin area specifically focussing on neuroregenerative applications in the central nervous system. In Chapter 2, there is an overview of the development of a potent analgesic compound that works via modulation of neuronal nicotinic acetylcholine receptors. In Chapter 3, there is a description of dopamine D-2 autoreceptor partial agonists as potential therapy for the treatment of schizophrenia. In Chapter 4, there is a summary of the successful program in which potent non-peptide inhibitors of HIV protease from the AIDS virus were developed.
    電子資源: http://www.sciencedirect.com/science/book/9780762305933
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