Handbook of the behavioral neurobiol...
Jacobs, Barry L.

 

  • Handbook of the behavioral neurobiology of serotonin[electronic resource] /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 612.8042
    書名/作者: Handbook of the behavioral neurobiology of serotonin/ edited by Christian P. M�uller and Barry L. Jacobs.
    其他作者: M�uller, Christian Peter.
    出版者: London : : Academic Press,, 2010.
    面頁冊數: xv, 818 p. : : ill., col. plates ;; 29 cm.
    標題: Serotonin - Physiological effect.
    標題: Neural transmission.
    標題: Neurochemistry.
    ISBN: 9780123746344
    ISBN: 0123746345
    書目註: Includes bibliographical references and index.
    內容註: Section 1: Functional anatomy of the serotonergic system Evolution of serotonin : sunlight to suicide / Efrain C. Azmitia -- Genetic organisation of the serotonergic system / Ursula M. D'Souza and Ian W. Craig -- The neuronatomy of the serotonergic system / Jean-Pierre Hornung -- Ultrastructure of the serotonin innervation in mammalian central nervous system / Laurent Descarries, Mustapha Riad and Martin Parent -- Classification and signaling characteristics of 5-HT receptors Joel Bockaert, Sylvie Claeysen, Aline Dumuis and Philippe Marin -- Distribution of 5-HT receptors in the central nervous system / Guadalupe Mengod, Roser Cort s, M. Teresa Vilar and Daniel Hoyer -- Measuring serotonin activity in vivo in the brains of animals and humans / Charles A Marsden -- Section 2: The neurophysiology of serotonin : Activity of brain serotonergic neurons in relation to physiology and behavior / Barry L. Jacobs and Casimir A. Fornal -- Electrophysiology of serotonin receptors / Gerard J. Marek -- Tryptophane hydroxylase and serotonin synthesis regulation / Hiroyuki Hasegawa and Kazuhiro Nakamura -- The degradation of serotonin : role of MAO / Marco Bortolato, Kevin Chen and Jean C Shih -- Cellular effects of serotonin in the CNS / Rodrigo Andrade and Sheryl G. Beck -- Serotonergic feedback control / Trevor Sharp -- Tryptophan depletion and serotonin release : a critical reappraisal / Matthijs G.P. Feenstra and Geoffrey van der Plasse -- Serotonin interaction with other transmitter systems / Albert Adell, Anal a Bortolozzi, Llorenc D iaz-Mataix, Noem Santana, Pau Celada, and Francesc Artigas -- Serotonergic regulation of rhythmical activity of the brain, concentrating on the hippocampus / Robert P. Vertes -- 5-HT neurons and central CO 2 chemoreception / Carolin I. Dohle and George B. Richerson --
    摘要、提要註: Serotonin (5-hydroxytryptamine, often cited as 5-HT) is one of the major excitatory neurotransmitter, and the serotonergic system is one of the best studied and understood transmitter systems. It is crucially involved in the organization of virtually all behaviours and in the regulation of emotion and mood. Alterations in the serotonergic system, induced by e.g. learning or pathological processes, underlie behavioural plasticity and changes in mood, which can finally results in abnormal behaviour and psychiatric conditions. Not surprisingly, the serotonergic system and its functional components appear to be targets for a multitude of pharmacological treatments - examples of very successful drugs targeting the serotoninergic system include Prozac and Zoloft. The last decades of research have not only fundamentally expanded our view on serotonin but also revealed in much more detail an astonishing complexity of this system, which comprises a multitude of receptors and signalling pathways. A detailed view on its role in basal, but also complex, behaviours emerged, and, was presented in a number of single review articles. Although much is known now, the serotonergic system is still a fast growing field of research contributing to our present understanding of the brains function during normal and disturbed behaviour. This handbook aims towards a detailed and comprehensive overview over the many facets of behavioural serotonin research. As such, it will provide the most up to date and thorough reading concerning the serotonergic systems control of behaviour and mood in animals and humans. The goal is to create a systematic overview and first hand reference that can be used by students and scholars alike in the fields of genetics, anatomy, pharmacology, physiology, behavioural neuroscience, pathology, and psychiatry. The chapters in this book will be written by leading scientists in this field. Most of them have already written excellent reviews in their field of expertise. The book is divided in 4 sections. After an historical introduction, illustrating the growth of ideas about serotonin function in behaviour of the last forty years, section A will focus on the functional anatomy of the serotonergic system. Section B provides a review of the neurophysiology of the serotonergic system and its single components. In section C the involvement of serotonin in behavioural organization will be discussed in great detail, while section D deals with the role of serotonin in behavioural pathologies and psychiatric disorders.
    電子資源: An electronic book accessible through the World Wide Web; click for information
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