大葉大學圖書館 |

Genetic diseases of the kidney[electronic resource] /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
杜威分類號:	616.61042
書名/作者:	Genetic diseases of the kidney/ edited by Richard P. Lifton ... [et al.].
其他作者:	Lifton, Richard P.
出版者:	Amsterdam ; : Elsevier/Academic Press,, 2009.
面頁冊數:	xiv, 829 p., [50] p. of plates : : ill. (some col.) ;; 28 cm.
標題:	Kidneys - Diseases
標題:	Kidney Diseases - genetics.
標題:	Kidney Diseases - physiopathology.
ISBN:	9780124498518
ISBN:	0124498515
書目註:	Includes bibliographical references and index.
摘要、提要註:	Genetic Diseases of the Kidney identifies and analyzes genetic abnormalities causing renal diseases in human subjects. Although in a sense the genome contains all the instructions required for the formation of a phenotype, the information is encoded in an extremely complicated fashion. In primary genetic diseases, the genetic instruction specifies a phenotype clearly linked with a discreet lesion confined to the kidney. However, the genetic disturbance may be imbedded in a complicated physiologic ensemble, so that the nexus between the genetic disturbance and the phenotype may be obscured; in consequence, the causal sequence is extremely difficult to unravel. In many instances the renal disease is one component of a complicated systemic hereditary disease, either monogenic or polygenic. Indeed, renal disease may arise as the sum of minor inputs from many different, seemingly unrelated genes, so that the genetic contributions may be difficult to identify. Confounding the problem further are environmental influences, originating either in the chromosomal environment from modifier genes, or in the extra-chromosomal environmental from intrauterine or postnatal influences. These considerations have determined both the organization of the text as well as the detailed description of the genetic disorders and the physiologic derangements that emerge. * Lays the essential foundation of mammalian genetics principles for medical professionals with little to no background in genetics. Analyzes specific renal diseases - both monogenic disorders confined to the kidney as well as systemic diseases with renal involvement - and explains their genetic causes. World-renowned editors and authors offer expert frameworks for understanding the links between genes and complex clinical disorders (i.e., lupus, diabetes, HIV, and hypertension).
電子資源:	An electronic book accessible through the World Wide Web; click for information

Genetic diseases of the kidney[electronic resource] /
Genetic diseases of the kidney[electronic resource] /edited by Richard P. Lifton ... [et al.]. - 1st ed. - Amsterdam ;Elsevier/Academic Press,2009. - xiv, 829 p., [50] p. of plates :ill. (some col.) ;28 cm.

Includes bibliographical references and index.

Genetic Diseases of the Kidney identifies and analyzes genetic abnormalities causing renal diseases in human subjects. Although in a sense the genome contains all the instructions required for the formation of a phenotype, the information is encoded in an extremely complicated fashion. In primary genetic diseases, the genetic instruction specifies a phenotype clearly linked with a discreet lesion confined to the kidney. However, the genetic disturbance may be imbedded in a complicated physiologic ensemble, so that the nexus between the genetic disturbance and the phenotype may be obscured; in consequence, the causal sequence is extremely difficult to unravel. In many instances the renal disease is one component of a complicated systemic hereditary disease, either monogenic or polygenic. Indeed, renal disease may arise as the sum of minor inputs from many different, seemingly unrelated genes, so that the genetic contributions may be difficult to identify. Confounding the problem further are environmental influences, originating either in the chromosomal environment from modifier genes, or in the extra-chromosomal environmental from intrauterine or postnatal influences. These considerations have determined both the organization of the text as well as the detailed description of the genetic disorders and the physiologic derangements that emerge. * Lays the essential foundation of mammalian genetics principles for medical professionals with little to no background in genetics. Analyzes specific renal diseases - both monogenic disorders confined to the kidney as well as systemic diseases with renal involvement - and explains their genetic causes. World-renowned editors and authors offer expert frameworks for understanding the links between genes and complex clinical disorders (i.e., lupus, diabetes, HIV, and hypertension).

Electronic reproduction.
Amsterdam :
Elsevier Science & Technology,
2009.

Mode of access: World Wide Web.

ISBN: 9780124498518

Source: 97502:97505Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:

427906
Kidneys
--DiseasesIndex Terms--Genre/Form:

336502
Electronic books.

LC Class. No.: RC903 / .G46 2009

Dewey Class. No.: 616.61042

National Library of Medicine Call No.: 2009 B-993

Genetic diseases of the kidney[electronic resource] /
LDR:03438cam 2200373Ia 4500 001 346842
003 OCoLC
005 20110614113910.0
006 m d
007 cr cn|||||||||
008 111130s2009 ne af ob 001 0 eng d
019 $a 370375719
020 $a 9780124498518
020 $a 0124498515
029 1 $a HEBIS $b 246724390
035 $a (OCoLC)318327985 $z (OCoLC)370375719
035 $a ocn318327985
037 $a 97502:97505 $b Elsevier Science & Technology $n http://www.sciencedirect.com
040 $a OPELS $b eng $c OPELS $d BTCTA
049 $a TEFA
050 1 4 $a RC903 $b .G46 2009
060 1 4 $a 2009 B-993
060 1 4 $a WJ 300 $b G3277 2009
082 0 4 $a 616.61042 $2 22
245 0 0 $a Genetic diseases of the kidney $h [electronic resource] / $c edited by Richard P. Lifton ... [et al.].
250 $a 1st ed.
260 $a Amsterdam ; $a Boston : $b Elsevier/Academic Press, $c 2009.
300 $a xiv, 829 p., [50] p. of plates : $b ill. (some col.) ; $c 28 cm.
504 $a Includes bibliographical references and index.
520 $a Genetic Diseases of the Kidney identifies and analyzes genetic abnormalities causing renal diseases in human subjects. Although in a sense the genome contains all the instructions required for the formation of a phenotype, the information is encoded in an extremely complicated fashion. In primary genetic diseases, the genetic instruction specifies a phenotype clearly linked with a discreet lesion confined to the kidney. However, the genetic disturbance may be imbedded in a complicated physiologic ensemble, so that the nexus between the genetic disturbance and the phenotype may be obscured; in consequence, the causal sequence is extremely difficult to unravel. In many instances the renal disease is one component of a complicated systemic hereditary disease, either monogenic or polygenic. Indeed, renal disease may arise as the sum of minor inputs from many different, seemingly unrelated genes, so that the genetic contributions may be difficult to identify. Confounding the problem further are environmental influences, originating either in the chromosomal environment from modifier genes, or in the extra-chromosomal environmental from intrauterine or postnatal influences. These considerations have determined both the organization of the text as well as the detailed description of the genetic disorders and the physiologic derangements that emerge. * Lays the essential foundation of mammalian genetics principles for medical professionals with little to no background in genetics. Analyzes specific renal diseases - both monogenic disorders confined to the kidney as well as systemic diseases with renal involvement - and explains their genetic causes. World-renowned editors and authors offer expert frameworks for understanding the links between genes and complex clinical disorders (i.e., lupus, diabetes, HIV, and hypertension).
533 $a Electronic reproduction. $b Amsterdam : $c Elsevier Science & Technology, $d 2009. $n Mode of access: World Wide Web. $n System requirements: Web browser. $n Title from title screen (viewed on Apr. 10, 2009). $n Access may be restricted to users at subscribing institutions.
650 0 $a Kidneys $x Diseases $x Genetic aspects. $3 427906
650 1 2 $a Kidney Diseases $x genetics. $3 427907
650 2 2 $a Kidney Diseases $x physiopathology. $3 427908
655 7 $a Electronic books. $2 local $3 336502
700 1 $a Lifton, Richard P. $3 427905
710 2 $a ScienceDirect (Online service) $3 365609
776 1 $c Original $z 9780124498518 $z 0124498515 $w (OCoLC)253210872
856 4 0 $3 ScienceDirect $u http://www.sciencedirect.com/science/book/9780124498518 $z An electronic book accessible through the World Wide Web; click for information
938 $a Baker and Taylor $b BTCP $n BK0007846699
994 $a C0 $b TEF