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Therapeutic applications of quadrupl...

Neidle, Stephen.

Therapeutic applications of quadruplex nucleic acids /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
杜威分類號:	615.36
書名/作者:	Therapeutic applications of quadruplex nucleic acids // Stephen Neidle.
作者:	Neidle, Stephen.
出版者:	London ; : Elsevier/Academic Press,, 2012.
面頁冊數:	xii, 196 p. : : ill. ;; 24 cm.
標題:	Quadruplex nucleic acids - Therapeutic use.
ISBN:	9780123751386 (hbk.) :
ISBN:	0123751381 (hbk.)
書目註:	Includes bibliographical references and index.
內容註:	Introduction: quadruplexes and their biology -- DNA and RNA quadruplex structures -- The structures of human telomeric DNA quadruplexes -- Telomeric quadruplex ligands I: anthraquinones and acridines -- Telomeric quadruplex ligands II: polycyclic and non-fused ring compounds -- The biology and pharmacology of telomeric quadruplex ligands -- Genomic quadruplexes as therapeutic targets -- RNA quadruplexes -- Design principles for quadruplex-binding small molecules -- The determination of quadruplex structures.
摘要、提要註:	"Therapeutic applications of quadruplex nucleic acids provides a single comprehensive survey that describes and assesses recent advances in quadruplex therapeutics and targeting strategies. It also covers the underlying fundamentals of such topics as quadruplex structure, small-molecule recognition, biological roles of genomic quadruplexes, and quadruplex informatics"--P. [4] of cover.

Therapeutic applications of quadruplex nucleic acids /
Neidle, Stephen.

Therapeutic applications of quadruplex nucleic acids /Stephen Neidle. - 1st ed. - London ;Elsevier/Academic Press,2012. - xii, 196 p. :ill. ;24 cm.

Includes bibliographical references and index.

Introduction: quadruplexes and their biology -- DNA and RNA quadruplex structures -- The structures of human telomeric DNA quadruplexes -- Telomeric quadruplex ligands I: anthraquinones and acridines -- Telomeric quadruplex ligands II: polycyclic and non-fused ring compounds -- The biology and pharmacology of telomeric quadruplex ligands -- Genomic quadruplexes as therapeutic targets -- RNA quadruplexes -- Design principles for quadruplex-binding small molecules -- The determination of quadruplex structures.

"Therapeutic applications of quadruplex nucleic acids provides a single comprehensive survey that describes and assesses recent advances in quadruplex therapeutics and targeting strategies. It also covers the underlying fundamentals of such topics as quadruplex structure, small-molecule recognition, biological roles of genomic quadruplexes, and quadruplex informatics"--P. [4] of cover.

ISBN: 9780123751386 (hbk.) :NTD 3,811

LCCN: 2011293620

Nat. Bib. No.: GBB198738bnb

Nat. Bib. Agency Control No.: 015873824UkSubjects--Topical Terms:

456003
Quadruplex nucleic acids
--Therapeutic use.

LC Class. No.: RM666.N87 / N45 2012

Dewey Class. No.: 615.36

Therapeutic applications of quadruplex nucleic acids /
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520 $a "Therapeutic applications of quadruplex nucleic acids provides a single comprehensive survey that describes and assesses recent advances in quadruplex therapeutics and targeting strategies. It also covers the underlying fundamentals of such topics as quadruplex structure, small-molecule recognition, biological roles of genomic quadruplexes, and quadruplex informatics"--P. [4] of cover.
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