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[ subject:"Imunologia celular." ]
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Molecular biology of B cells[electro...
~
Alt, Frederick W.
Molecular biology of B cells[electronic resource] /
紀錄類型:
書目-語言資料,印刷品 : Monograph/item
杜威分類號:
616.07/98
書名/作者:
Molecular biology of B cells/ edited by Tasuku Honjo, Frederick W. Alt, Michael S. Neuberger.
其他作者:
Honjo, T.
出版者:
Amsterdam ; : Elsevier,, 2004.
面頁冊數:
xiv, 589 p. : : col. ill. ;; 29 cm.
標題:
Molecular immunology.
標題:
B cells.
標題:
Immunoglobulins.
標題:
Immunoglobulin genes.
標題:
B-Lymphocytes - immunology.
標題:
Genes, Immunoglobulin.
標題:
Genetic Processes.
標題:
Linf�ocitos b.
標題:
Imunologia celular.
標題:
Imunoglobulinas.
標題:
Biologia molecular.
標題:
Immunologie mol�eculaire.
標題:
Lymphocytes B.
標題:
Immunoglobulines.
標題:
G�enes de l'immunoglobuline.
ISBN:
9780120536412
ISBN:
0120536412
書目註:
Includes bibliographical references and index.
內容註:
ORGANIZATION, REARRANGEMENT AND TRANSCRIPTION OF IMMUNOGLOBULIN GENES -- Human Immunoglobulin heavy chains locus -- Immunoglobulin heavy chain genes of mouse -- Immunoglobulin? genes of human and mouse -- Immunoglobulin lambdav (IGL) genes of human and mouse -- The Mechanism of V(D) J Recombination -- Transcription of Immunoglobulin genes -- B CELLS AND THEIR DEVELOPMENT -- Early B cell development to a mature, antigen-sensitive cell -- cellular stages and molecular decisions -- Allelic exclusion, Isotypic exclusion and the Developmental Regulation of V(D)J Recombination -- The Development of Human B Lymphocytes -- Development and function of B cell subsets -- B CELL DIFFERENTIATION INDUCED BY Ag STIMULATION -- Structure and function of B cells antigen receptor complexes -- Regulation of antigen receptor signaling by the co-receptors, CD19 and CD22 -- The dynamic structure of antibody responses -- Dynamics of B cell migration to and within secondary lymphoid organs -- Characteristics of mucosal B cells with emphasis on the human secretory immune system -- The Cellular Basis of B Cell Memory -- Immunoglobulin assembly and secretion -- Fc And Complement Receptors -- Ig GENE ALTERATION IN PERIPHERY -- Regulation of Class Switch Recombination -- Molecular Mechanism of Class Switch Recombination -- Molecular Mechanism of Hypermutation -- Selection During Antigen-Driven B Cell Immune Responses: The Basis for High Affinity Antibody -- DISEASES OF B CELLS -- Chromosomal Translocations in B-cell Leukemias and Lymphomas -- Classification and Characteristics of Mouse B Cell-Lineage Lymphomas -- B cells producing pathogenic autoantibodies -- Immunodeficiencies Caused by B Cell Defects -- EVOLUTION OF Ig GENES -- Diverse forms of Immunoglobulin Genes in Lower Vertebrates -- Immunoglobulin Genes and Generation of Antibody Repertoires in Higher Vertebrates: A Key Role for GALT -- The zebrafish immune system -- The Origin of V(D)J Diversification -- FUNCTION AND APPLICATION OF IMMUNOGLOBULINS -- Antibody Structure and Recognition of Antigen -- Monoclonal antibodies from display libraries -- Humanization of Monoclonal Antibodies -- Human monoclonal antibodies from translocus mice.
摘要、提要註:
Molecular Biology of B Cells is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described in molecular and genetic terms to give a clear understanding of complex phenotyes. The molecular basis of many diseases due to B cell abnormality is also discussed. This definitive reference is directed at research level immunologists, molecular biologists and geneticists.
電子資源:
An electronic book accessible through the World Wide Web; click for information
Molecular biology of B cells[electronic resource] /
Molecular biology of B cells
[electronic resource] /edited by Tasuku Honjo, Frederick W. Alt, Michael S. Neuberger. - Amsterdam ;Elsevier,2004. - xiv, 589 p. :col. ill. ;29 cm.
Includes bibliographical references and index.
ORGANIZATION, REARRANGEMENT AND TRANSCRIPTION OF IMMUNOGLOBULIN GENES -- Human Immunoglobulin heavy chains locus -- Immunoglobulin heavy chain genes of mouse -- Immunoglobulin? genes of human and mouse -- Immunoglobulin lambdav (IGL) genes of human and mouse -- The Mechanism of V(D) J Recombination -- Transcription of Immunoglobulin genes -- B CELLS AND THEIR DEVELOPMENT -- Early B cell development to a mature, antigen-sensitive cell -- cellular stages and molecular decisions -- Allelic exclusion, Isotypic exclusion and the Developmental Regulation of V(D)J Recombination -- The Development of Human B Lymphocytes -- Development and function of B cell subsets -- B CELL DIFFERENTIATION INDUCED BY Ag STIMULATION -- Structure and function of B cells antigen receptor complexes -- Regulation of antigen receptor signaling by the co-receptors, CD19 and CD22 -- The dynamic structure of antibody responses -- Dynamics of B cell migration to and within secondary lymphoid organs -- Characteristics of mucosal B cells with emphasis on the human secretory immune system -- The Cellular Basis of B Cell Memory -- Immunoglobulin assembly and secretion -- Fc And Complement Receptors -- Ig GENE ALTERATION IN PERIPHERY -- Regulation of Class Switch Recombination -- Molecular Mechanism of Class Switch Recombination -- Molecular Mechanism of Hypermutation -- Selection During Antigen-Driven B Cell Immune Responses: The Basis for High Affinity Antibody -- DISEASES OF B CELLS -- Chromosomal Translocations in B-cell Leukemias and Lymphomas -- Classification and Characteristics of Mouse B Cell-Lineage Lymphomas -- B cells producing pathogenic autoantibodies -- Immunodeficiencies Caused by B Cell Defects -- EVOLUTION OF Ig GENES -- Diverse forms of Immunoglobulin Genes in Lower Vertebrates -- Immunoglobulin Genes and Generation of Antibody Repertoires in Higher Vertebrates: A Key Role for GALT -- The zebrafish immune system -- The Origin of V(D)J Diversification -- FUNCTION AND APPLICATION OF IMMUNOGLOBULINS -- Antibody Structure and Recognition of Antigen -- Monoclonal antibodies from display libraries -- Humanization of Monoclonal Antibodies -- Human monoclonal antibodies from translocus mice.
Molecular Biology of B Cells is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described in molecular and genetic terms to give a clear understanding of complex phenotyes. The molecular basis of many diseases due to B cell abnormality is also discussed. This definitive reference is directed at research level immunologists, molecular biologists and geneticists.
Electronic reproduction.
Amsterdam :
Elsevier Science & Technology,
2007.
Mode of access: World Wide Web.
ISBN: 9780120536412
Source: 97397:97398Elsevier Science & Technologyhttp://www.sciencedirect.comSubjects--Topical Terms:
428435
Molecular immunology.
Index Terms--Genre/Form:
336502
Electronic books.
LC Class. No.: QR185.6 / .M653 2004eb
Dewey Class. No.: 616.07/98
National Library of Medicine Call No.: 2004 B-470
Molecular biology of B cells[electronic resource] /
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ORGANIZATION, REARRANGEMENT AND TRANSCRIPTION OF IMMUNOGLOBULIN GENES -- Human Immunoglobulin heavy chains locus -- Immunoglobulin heavy chain genes of mouse -- Immunoglobulin? genes of human and mouse -- Immunoglobulin lambdav (IGL) genes of human and mouse -- The Mechanism of V(D) J Recombination -- Transcription of Immunoglobulin genes -- B CELLS AND THEIR DEVELOPMENT -- Early B cell development to a mature, antigen-sensitive cell -- cellular stages and molecular decisions -- Allelic exclusion, Isotypic exclusion and the Developmental Regulation of V(D)J Recombination -- The Development of Human B Lymphocytes -- Development and function of B cell subsets -- B CELL DIFFERENTIATION INDUCED BY Ag STIMULATION -- Structure and function of B cells antigen receptor complexes -- Regulation of antigen receptor signaling by the co-receptors, CD19 and CD22 -- The dynamic structure of antibody responses -- Dynamics of B cell migration to and within secondary lymphoid organs -- Characteristics of mucosal B cells with emphasis on the human secretory immune system -- The Cellular Basis of B Cell Memory -- Immunoglobulin assembly and secretion -- Fc And Complement Receptors -- Ig GENE ALTERATION IN PERIPHERY -- Regulation of Class Switch Recombination -- Molecular Mechanism of Class Switch Recombination -- Molecular Mechanism of Hypermutation -- Selection During Antigen-Driven B Cell Immune Responses: The Basis for High Affinity Antibody -- DISEASES OF B CELLS -- Chromosomal Translocations in B-cell Leukemias and Lymphomas -- Classification and Characteristics of Mouse B Cell-Lineage Lymphomas -- B cells producing pathogenic autoantibodies -- Immunodeficiencies Caused by B Cell Defects -- EVOLUTION OF Ig GENES -- Diverse forms of Immunoglobulin Genes in Lower Vertebrates -- Immunoglobulin Genes and Generation of Antibody Repertoires in Higher Vertebrates: A Key Role for GALT -- The zebrafish immune system -- The Origin of V(D)J Diversification -- FUNCTION AND APPLICATION OF IMMUNOGLOBULINS -- Antibody Structure and Recognition of Antigen -- Monoclonal antibodies from display libraries -- Humanization of Monoclonal Antibodies -- Human monoclonal antibodies from translocus mice.
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