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First in fly :Drosophila research an...

Mohr, Stephanie Elizabeth, (1971-)

First in fly :Drosophila research and biological discovery /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
杜威分類號:	595.77/4
書名/作者:	First in fly : : Drosophila research and biological discovery // Stephanie Elizabeth Mohr.
作者:	Mohr, Stephanie Elizabeth,
出版者:	Cambridge, Mass. : : Harvard University Press,, 2018.
面頁冊數:	xii, 257 p. : : ill. ;; 25 cm.
標題:	Drosophila melanogaster - Genetics.
標題:	Drosophila melanogaster - Physiology.
標題:	Animal models in research.
ISBN:	9780674971011 (hbk.) :
書目註:	Includes bibliographical references (p. [205]-248) and index.
內容註:	Maps -- Change -- Communication -- Size -- Direction -- Difference -- Defenses -- Behavior -- Coordination -- Continuity.
摘要、提要註:	A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. Written by a leader in the Drosophila research community, 1st in Fly celebrates key insights uncovered by investigators using this model organism. Stephanie Elizabeth Mohr draws on these "1st in fly" findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease.--

First in fly :Drosophila research and biological discovery /
Mohr, Stephanie Elizabeth,1971-

First in fly :Drosophila research and biological discovery /Stephanie Elizabeth Mohr. - Cambridge, Mass. :Harvard University Press,2018. - xii, 257 p. :ill. ;25 cm.

Includes bibliographical references (p. [205]-248) and index.

Maps -- Change -- Communication -- Size -- Direction -- Difference -- Defenses -- Behavior -- Coordination -- Continuity.

A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. Written by a leader in the Drosophila research community, 1st in Fly celebrates key insights uncovered by investigators using this model organism. Stephanie Elizabeth Mohr draws on these "1st in fly" findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease.--

ISBN: 9780674971011 (hbk.) :NTD 1,096

LCCN: 2017039271Subjects--Topical Terms:

694388
Drosophila melanogaster
--Genetics.

LC Class. No.: QL537.D76 / M65 2018

Dewey Class. No.: 595.77/4

First in fly :Drosophila research and biological discovery /
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300 $a xii, 257 p. : $b ill. ; $c 25 cm.
504 $a Includes bibliographical references (p. [205]-248) and index.
505 0 $a Maps -- Change -- Communication -- Size -- Direction -- Difference -- Defenses -- Behavior -- Coordination -- Continuity.
520 $a A single species of fly, Drosophila melanogaster, has been the subject of scientific research for more than one hundred years. Why does this tiny insect merit such intense scrutiny? Drosophila's importance as a research organism began with its short life cycle, ability to reproduce in large numbers, and easy-to-see mutant phenotypes. Over time, laboratory investigation revealed surprising similarities between flies and other animals at the level of genes, gene networks, cell interactions, physiology, immunity, and behavior. Like humans, flies learn and remember, fight microbial infection, and slow down as they age. Scientists use Drosophila to investigate complex biological activities in a simple but intact living system. Fly research provides answers to some of the most challenging questions in biology and biomedicine, including how cells transmit signals and form ordered structures, how we can interpret the wealth of human genome data now available, and how we can develop effective treatments for cancer, diabetes, and neurodegenerative diseases. Written by a leader in the Drosophila research community, 1st in Fly celebrates key insights uncovered by investigators using this model organism. Stephanie Elizabeth Mohr draws on these "1st in fly" findings to introduce fundamental biological concepts gained over the last century and explore how research in the common fruit fly has expanded our understanding of human health and disease.-- $c Provided by publisher
650 0 $a Drosophila melanogaster $x Genetics. $3 694388
650 0 $a Drosophila melanogaster $x Physiology. $3 694389
650 0 $a Animal models in research. $3 428755