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Epigenetic technological applications[electronic resource] /

紀錄類型:	書目-電子資源 : Monograph/item
杜威分類號:	572.8/65
書名/作者:	Epigenetic technological applications/ edited by Y. George Zheng.
其他作者:	Zheng, Y. George.
出版者:	Amsterdam : : Academic Press,, c2015.
面頁冊數:	1 online resource (xxiii, 491 p., [18] p. of plates) : : ill. (some col.)
標題:	Epigenetics - Data processing.
標題:	Epigenetics - Research
標題:	Epigenomics.
ISBN:	9780128010808 (electronic bk.)
ISBN:	0128010800 (electronic bk.)
書目註:	Includes bibliographical references and index.
內容註:	The state of the art of epigenetic technologies -- Technologies for the measurement and mapping of genomic 5-methylcytosine and 5-hydroxymethylcytosine -- High-throughput sequencing-based mapping of cytosine modifications -- Application of mass spectrometry in translational epigenetics -- Techniques analyzing chromatin modifications at specific single loci -- Comprehensive analysis of mammalian linker-histone variants and their mutants -- Crystallography-based mechanistic insights into epigenetic regulation -- Chemical and genetic approaches to study histone modifications -- Peptide microarrays for profiling of epigenetic targets -- Current methods for methylome profiling -- Bioinformatics and biostatistics in mining epigenetic disease markers and targets -- Computational modeling to elucidate molecular mechanisms of epigenetic memory -- DNA methyltransferase inhibitors for cancer therapy -- Histone acetyltransferases: enzymes, assays, and inhibitors -- In vitro histone deacetylase activity screening: making a case for better assays -- Enzymatic assays of histone methyltransferase enzymes -- Histone methyltransferase inhibitors for cancer therapy -- Discovery of histone demethylase inhibitors -- Histone demethylases: background, purification, and detection -- Animal model study of epigenetic inhibitors -- Index.
電子資源:	click for full text

Epigenetic technological applications[electronic resource] /
Epigenetic technological applications[electronic resource] /edited by Y. George Zheng. - Amsterdam :Academic Press,c2015. - 1 online resource (xxiii, 491 p., [18] p. of plates) :ill. (some col.) - Translational epigenetics series. - Translational epigenetics series..

Includes bibliographical references and index.

The state of the art of epigenetic technologies -- Technologies for the measurement and mapping of genomic 5-methylcytosine and 5-hydroxymethylcytosine -- High-throughput sequencing-based mapping of cytosine modifications -- Application of mass spectrometry in translational epigenetics -- Techniques analyzing chromatin modifications at specific single loci -- Comprehensive analysis of mammalian linker-histone variants and their mutants -- Crystallography-based mechanistic insights into epigenetic regulation -- Chemical and genetic approaches to study histone modifications -- Peptide microarrays for profiling of epigenetic targets -- Current methods for methylome profiling -- Bioinformatics and biostatistics in mining epigenetic disease markers and targets -- Computational modeling to elucidate molecular mechanisms of epigenetic memory -- DNA methyltransferase inhibitors for cancer therapy -- Histone acetyltransferases: enzymes, assays, and inhibitors -- In vitro histone deacetylase activity screening: making a case for better assays -- Enzymatic assays of histone methyltransferase enzymes -- Histone methyltransferase inhibitors for cancer therapy -- Discovery of histone demethylase inhibitors -- Histone demethylases: background, purification, and detection -- Animal model study of epigenetic inhibitors -- Index.

ISBN: 9780128010808 (electronic bk.)Subjects--Topical Terms:

659140
Epigenetics
--Data processing.

LC Class. No.: QH450 / .E6535 2015

Dewey Class. No.: 572.8/65

Epigenetic technological applications[electronic resource] /
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245 0 0 $a Epigenetic technological applications $h [electronic resource] / $c edited by Y. George Zheng.
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490 1 $a Translational epigenetics series
504 $a Includes bibliographical references and index.
505 0 $a The state of the art of epigenetic technologies -- Technologies for the measurement and mapping of genomic 5-methylcytosine and 5-hydroxymethylcytosine -- High-throughput sequencing-based mapping of cytosine modifications -- Application of mass spectrometry in translational epigenetics -- Techniques analyzing chromatin modifications at specific single loci -- Comprehensive analysis of mammalian linker-histone variants and their mutants -- Crystallography-based mechanistic insights into epigenetic regulation -- Chemical and genetic approaches to study histone modifications -- Peptide microarrays for profiling of epigenetic targets -- Current methods for methylome profiling -- Bioinformatics and biostatistics in mining epigenetic disease markers and targets -- Computational modeling to elucidate molecular mechanisms of epigenetic memory -- DNA methyltransferase inhibitors for cancer therapy -- Histone acetyltransferases: enzymes, assays, and inhibitors -- In vitro histone deacetylase activity screening: making a case for better assays -- Enzymatic assays of histone methyltransferase enzymes -- Histone methyltransferase inhibitors for cancer therapy -- Discovery of histone demethylase inhibitors -- Histone demethylases: background, purification, and detection -- Animal model study of epigenetic inhibitors -- Index.
650 0 $a Epigenetics $x Data processing. $3 659140
650 0 $a Epigenetics $x Research $x Methodology. $3 659141
650 1 2 $a Epigenomics. $3 553321
700 1 $a Zheng, Y. George. $3 659139
830 0 $a Translational epigenetics series. $3 659028
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