Receptor tyrosine kinases[electronic...
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  • Receptor tyrosine kinases[electronic resource] :family and subfamilies /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 572.6696
    書名/作者: Receptor tyrosine kinases : family and subfamilies // edited by Deric L. Wheeler, Yosef Yarden.
    其他作者: Wheeler, Deric L.
    出版者: Cham : : Springer International Publishing :, 2015.
    面頁冊數: xvii, 878 p. : : ill. (some col.), digital ;; 24 cm.
    Contained By: Springer eBooks
    標題: Protein-tyrosine kinase - Receptors.
    標題: Life Sciences.
    標題: Cell Biology.
    標題: Receptors.
    標題: Pharmaceutical Sciences/Technology.
    ISBN: 9783319118888 (electronic bk.)
    ISBN: 9783319118871 (paper)
    內容註: Anaplastic Lymphoma Kinase (ALK) Receptor Tyrosine Kinase (RTK) Family -- The TAM Receptor Family -- DDR Receptor Tyrosine Kinase Family -- EGFR/ERBB Receptor Tyrosine Kinase Family -- Eph Receptor Tyrosine Kinase Family -- Receptor Tyrosine Kinase textbook - Fibroblast Growth Factor Receptor (FGFR) -- Insulin/IGF1 Receptors (INSR/IGF1R) Family -- MET Receptor Tyrosine Kinase Family -- MuSK Receptor Family -- The PDGFR Receptor Family -- PTK7 Receptor Tyrosine Kinase Family -- RET Receptor Tyrosine Kinase -- ROR Receptor Tyrosine Kinase Family -- ROS1 Receptor Tyrosine Kinase -- The RYK Receptor Tyrosine Kinase Subfamily -- TIE Receptor Tyrosine Kinase Family -- TRK Receptor Family -- The VEGF Family of Ligands and Receptors -- NOK Receptor Tyrosine Kinase Family.
    摘要、提要註: Receptor tyrosine kinases (RTKs) play critical roles in embryogenesis, normal physiology and several diseases, and over the last decade have become the number one targets of cancer drugs. Receptor Tyrosine Kinase: Family and Subfamilies systematically covers, for the first time, the shared structural and functional features of the RTK family. Understanding the evolutionary origin of the fifty-eight RTKs, their roles in invertebrates and in humans, as well as downstream signaling pathways, is essential for fundamental research and for attempts to develop pharmacological agents able to enhance or intercept their actions. The assembly of chapters written by experts underscores commonalities and is an ideal companion volume to Receptor Tyrosine Kinases: Structure, Functions and Role in Human Disease, which refers to specific subfamilies of RTKs, along with their unique landmarks.
    電子資源: http://dx.doi.org/10.1007/978-3-319-11888-8
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