Protein-ligand interactions[electron...
Gohlke, Holger.

 

  • Protein-ligand interactions[electronic resource] /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 615.19
    書名/作者: Protein-ligand interactions/ edited by Holger Gohlke.
    其他作者: Gohlke, Holger.
    出版者: Weinheim : : Wiley-VCH,, ©2012.
    面頁冊數: 1 online resource (xx, 339 p.) : : ill.
    標題: Proteins.
    標題: Ligands (Biochemistry)
    標題: Ligand binding (Biochemistry)
    標題: Drugs - Structure-activity relationships.
    ISBN: 9783527645978 (electronic bk.)
    ISBN: 3527645977 (electronic bk.)
    ISBN: 3527329668
    ISBN: 9781280662898 (MyiLibrary)
    ISBN: 1280662891 (MyiLibrary)
    書目註: Includes bibliographical references and index.
    摘要、提要註: Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic understanding of the factors governing protein-ligand interaction, followed by a comparison of the four key experimental methods (calorimetry, surface plasmon resonance, NMR and X-ray crystallography) used in generating interaction data. The second half of the book is devoted to in-silico methods of modeling and predicting molecular recognition and binding. Here, as elsewhere in the book, emphasis is placed on novel approaches and recent improvements to established methods. The final part looks at unresolved challenges, and the strategies to address them.
    電子資源: http://onlinelibrary.wiley.com/book/10.1002/9783527645947
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