Lead optimization for medicinal chem...
Dörwald, Florencio Zaragoza.

 

  • Lead optimization for medicinal chemists[electronic resource] :pharmacokinetic properties of functional groups and organic compounds /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 615.19
    書名/作者: Lead optimization for medicinal chemists : pharmacokinetic properties of functional groups and organic compounds // Florencioa Zaragoza Dörwald.
    作者: Dörwald, Florencio Zaragoza.
    出版者: Weinheim : : Wiley-VCH Verlag GmBH & Co.,, 2012.
    面頁冊數: 1 online resource (xvi, 605 p.) : : ill.
    標題: Pharmaceutical chemistry.
    ISBN: 9783527645640 (electronic bk.)
    ISBN: 3527645640
    ISBN: 9783527645664
    ISBN: 3527645667
    書目註: Includes bibliographical references and index.
    內容註: pt. 1. Introduction -- pt. 2. The pharmacokinetic properties of compound classes.
    摘要、提要註: Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and sy.
    電子資源: http://onlinelibrary.wiley.com/book/10.1002/9783527645640
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