Genetic recombination in cancer[elec...
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  • Genetic recombination in cancer[electronic resource] /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 616.994042
    書名/作者: Genetic recombination in cancer/ G.V. Sherbet.
    作者: Sherbet, G. V.
    出版者: San Diego, Calif. : : Academic,, 2003.
    面頁冊數: 304 p. : : ill. ;; 23 cm.
    標題: Cancer - Genetic aspects.
    標題: Genetic recombination.
    標題: Neoplasms - genetics.
    標題: Neoplasm Metastasis.
    標題: Recombination, Genetic.
    ISBN: 9780126398816
    ISBN: 012639881X
    書目註: Includes bibliographical references and index.
    內容註: Genetic Integrity, DNA Repair and Recombination -- Replication Error (RER) and Genetic Instability -- DNA Repeats, Genetic Recombination and the Pathogenesis of Genetic Disorders -- Chromosomal Recombination in Cancer -- Chromosomal Translocation and its Phenotypic Outcome -- DNA Methylation and Genetic Instability -- Telomeric DNA and Genetic Instability.
    摘要、提要註: Genetic recombination is a process of combining genes that leads to the generation of cell variants that possess different characteristics. This process is important to the evolution of a species and to embryonic growth and differentiation. However, this process can also lead to the development of abnormal, cancerous cells. This book reviews the role of genetic recombination in the generation of various cancers and how genetic alterations have been or could be employed to elicit clinically useful information. * Provides detailed discussion of the genetic mechanisms that result in the generation of normal and abnormal cells * Examines the role of genetic recombination in cancer including cancer invasion and metastasis * Information is presented in a manner that is useful and accessible to everyone from graduate students to established cancer researchers.
    電子資源: An electronic book accessible through the World Wide Web; click for information
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