大葉大學圖書館 |

Structural bioinformatics tools for drug design[electronic resource] :extraction of biologically relevant information from structural databases /

紀錄類型:	書目-語言資料,印刷品 : Monograph/item
杜威分類號:	572.330285
書名/作者:	Structural bioinformatics tools for drug design : extraction of biologically relevant information from structural databases // by Jaroslav Koca ... [et al.].
其他作者:	Koca, Jaroslav.
出版者:	Cham : : Springer International Publishing :, 2016.
面頁冊數:	xiii, 144 p. : : ill., digital ;; 24 cm.
Contained By:	Springer eBooks
標題:	Structural bioinformatics.
標題:	Drugs - Design.
標題:	Biomedicine.
標題:	Biomedical Engineering/Biotechnology.
標題:	Bioinformatics.
標題:	Computational Biology/Bioinformatics.
ISBN:	9783319473888
ISBN:	9783319473871
內容註:	1. Introduction -- 2. Biomacromolecular fragments -- 3. Databases -- 4. Detection & Extraction -- a. Biomacromolecular fragments and structural patterns -- b. channels and pores -- 5. Validation -- 6. Characterization -- a. Partial atomic charges -- b. Channel characteristics -- 7. Selected Examples.
摘要、提要註:	A large amount of structural data on biomacromolecules is available and the number of resolved structures is growing rapidly. This implies that we have an increasing opportunity to perform so far unprecedented analyses to obtain crucial biological insight. Biomacromolecular structural fragments such as binding sites or active sites, ligands, channels, pores, secondary structure motifs, etc., become very promising objects for these analyses because such fragments often serve as drug targets or drug templates, or substrate-specific pathways. However, such analyses are very challenging due to their complexity and, consequently, also because they require application of a combination of different software tools. In this book, we describe individual steps necessary for analysis of biomacromolecular fragments and provide a lsit of software tools required to perform such steps. For each step, we also show corresponding web-based tools in detail and provide a few practical examples of their usage.
電子資源:	http://dx.doi.org/10.1007/978-3-319-47388-8

Structural bioinformatics tools for drug design[electronic resource] :extraction of biologically relevant information from structural databases /
Structural bioinformatics tools for drug designextraction of biologically relevant information from structural databases /[electronic resource] :by Jaroslav Koca ... [et al.]. - Cham :Springer International Publishing :2016. - xiii, 144 p. :ill., digital ;24 cm. - SpringerBriefs in biochemistry and molecular biology,2211-9353. - SpringerBriefs in biochemistry and molecular biology..

1. Introduction -- 2. Biomacromolecular fragments -- 3. Databases -- 4. Detection & Extraction -- a. Biomacromolecular fragments and structural patterns -- b. channels and pores -- 5. Validation -- 6. Characterization -- a. Partial atomic charges -- b. Channel characteristics -- 7. Selected Examples.

A large amount of structural data on biomacromolecules is available and the number of resolved structures is growing rapidly. This implies that we have an increasing opportunity to perform so far unprecedented analyses to obtain crucial biological insight. Biomacromolecular structural fragments such as binding sites or active sites, ligands, channels, pores, secondary structure motifs, etc., become very promising objects for these analyses because such fragments often serve as drug targets or drug templates, or substrate-specific pathways. However, such analyses are very challenging due to their complexity and, consequently, also because they require application of a combination of different software tools. In this book, we describe individual steps necessary for analysis of biomacromolecular fragments and provide a lsit of software tools required to perform such steps. For each step, we also show corresponding web-based tools in detail and provide a few practical examples of their usage.

ISBN: 9783319473888

Standard No.: 10.1007/978-3-319-47388-8doiSubjects--Topical Terms:

603867
Structural bioinformatics.

LC Class. No.: QH324.2

Dewey Class. No.: 572.330285

Structural bioinformatics tools for drug design[electronic resource] :extraction of biologically relevant information from structural databases /
LDR:02444nam a2200337 a 4500 001 477186
003 DE-He213
005 20170124120505.0
006 m d
007 cr nn 008maaau
008 181208s2016 gw s 0 eng d
020 $a 9783319473888 $q (electronic bk.)
020 $a 9783319473871 $q (paper)
024 7 $a 10.1007/978-3-319-47388-8 $2 doi
035 $a 978-3-319-47388-8
040 $a GP $c GP
041 0 $a eng
050 4 $a QH324.2
072 7 $a MQW $2 bicssc
072 7 $a MED003040 $2 bisacsh
072 7 $a MED009000 $2 bisacsh
082 0 4 $a 572.330285 $2 23
090 $a QH324.2 $b .S927 2016
245 0 0 $a Structural bioinformatics tools for drug design $h [electronic resource] : $b extraction of biologically relevant information from structural databases / $c by Jaroslav Koca ... [et al.].
260 $a Cham : $b Springer International Publishing : $b Imprint: Springer, $c 2016.
300 $a xiii, 144 p. : $b ill., digital ; $c 24 cm.
490 1 $a SpringerBriefs in biochemistry and molecular biology, $x 2211-9353
505 0 $a 1. Introduction -- 2. Biomacromolecular fragments -- 3. Databases -- 4. Detection & Extraction -- a. Biomacromolecular fragments and structural patterns -- b. channels and pores -- 5. Validation -- 6. Characterization -- a. Partial atomic charges -- b. Channel characteristics -- 7. Selected Examples.
520 $a A large amount of structural data on biomacromolecules is available and the number of resolved structures is growing rapidly. This implies that we have an increasing opportunity to perform so far unprecedented analyses to obtain crucial biological insight. Biomacromolecular structural fragments such as binding sites or active sites, ligands, channels, pores, secondary structure motifs, etc., become very promising objects for these analyses because such fragments often serve as drug targets or drug templates, or substrate-specific pathways. However, such analyses are very challenging due to their complexity and, consequently, also because they require application of a combination of different software tools. In this book, we describe individual steps necessary for analysis of biomacromolecular fragments and provide a lsit of software tools required to perform such steps. For each step, we also show corresponding web-based tools in detail and provide a few practical examples of their usage.
650 0 $a Structural bioinformatics. $3 603867
650 0 $a Drugs $x Design. $3 424032
650 1 4 $a Biomedicine. $3 463454
650 2 4 $a Biomedical Engineering/Biotechnology. $3 634467
650 2 4 $a Bioinformatics. $3 184439
650 2 4 $a Computational Biology/Bioinformatics. $3 463480
700 1 $a Koca, Jaroslav. $3 688532
710 2 $a SpringerLink (Online service) $3 463450
773 0 $t Springer eBooks
830 0 $a SpringerBriefs in biochemistry and molecular biology. $3 468725
856 4 0 $u http://dx.doi.org/10.1007/978-3-319-47388-8
950 $a Biomedical and Life Sciences (Springer-11642)