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[ author_sort:"powell, kimberley jade." ]
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Synthetic and biophysical studies on...
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Powell, Kimberley Jade.
Synthetic and biophysical studies on the tridachiahydropyrone family of natural products[electronic resource] /
紀錄類型:
書目-語言資料,印刷品 : Monograph/item
杜威分類號:
572
書名/作者:
Synthetic and biophysical studies on the tridachiahydropyrone family of natural products/ by Kimberley Jade Powell.
作者:
Powell, Kimberley Jade.
出版者:
Cham : : Springer International Publishing :, 2016.
面頁冊數:
xix, 136 p. : : ill., digital ;; 24 cm.
Contained By:
Springer eBooks
標題:
Natural products - Synthesis.
標題:
Metabolites.
標題:
Oxygen - Metabolism.
標題:
Chemistry.
標題:
Organic Chemistry.
標題:
Membranes.
標題:
Spectroscopy/Spectrometry.
ISBN:
9783319220697
ISBN:
9783319220680
內容註:
Introduction -- Synthesis of the Tridachiahydropyrones and their Biomimetic Precursors -- Interactions of the Tridachiahydropyrones with Model Membrane Systems: Biophysical Studies -- Investigations into the Photoprotective and Antioxidant Properties of the Tridachiahydropyrones -- Summary and Conclusions -- Experimental -- Synthesis of Alkenyl Nitriles by the Palladium-Catalysed Cyanation of Vinyl Halides with Acetone Cyanohydrin.
摘要、提要註:
This thesis addresses fundamental scientific questions such as: How are complex natural products synthesized in vivo? Can we replicate these conditions in a laboratory environment? What is the biological function of such secondary metabolites? What are the biological origins of chirality? These issues are explored in an accessible manner using a multidisciplinary approach spanning chemistry, biology and physics to investigate an interesting family of complex natural products isolated from marine molluscs - the tridachiahydropyrones. The work has achieved: Elegant biomimetic syntheses of a number of the tridachiahydropyrone compounds in vitro using organic synthesis techniques The characterization of the interactions between these compounds and a range of model membrane systems using a series of fluorescence spectroscopic studies The investigation of the antioxidant and photoprotective properties of the compounds by means of biophysical assay techniques The synthesis of tridachiahydropyrone utilizing the model membrane systems as biomimetic reaction media.
電子資源:
http://dx.doi.org/10.1007/978-3-319-22069-7
Synthetic and biophysical studies on the tridachiahydropyrone family of natural products[electronic resource] /
Powell, Kimberley Jade.
Synthetic and biophysical studies on the tridachiahydropyrone family of natural products
[electronic resource] /by Kimberley Jade Powell. - Cham :Springer International Publishing :2016. - xix, 136 p. :ill., digital ;24 cm. - Springer theses,2190-5053. - Springer theses..
Introduction -- Synthesis of the Tridachiahydropyrones and their Biomimetic Precursors -- Interactions of the Tridachiahydropyrones with Model Membrane Systems: Biophysical Studies -- Investigations into the Photoprotective and Antioxidant Properties of the Tridachiahydropyrones -- Summary and Conclusions -- Experimental -- Synthesis of Alkenyl Nitriles by the Palladium-Catalysed Cyanation of Vinyl Halides with Acetone Cyanohydrin.
This thesis addresses fundamental scientific questions such as: How are complex natural products synthesized in vivo? Can we replicate these conditions in a laboratory environment? What is the biological function of such secondary metabolites? What are the biological origins of chirality? These issues are explored in an accessible manner using a multidisciplinary approach spanning chemistry, biology and physics to investigate an interesting family of complex natural products isolated from marine molluscs - the tridachiahydropyrones. The work has achieved: Elegant biomimetic syntheses of a number of the tridachiahydropyrone compounds in vitro using organic synthesis techniques The characterization of the interactions between these compounds and a range of model membrane systems using a series of fluorescence spectroscopic studies The investigation of the antioxidant and photoprotective properties of the compounds by means of biophysical assay techniques The synthesis of tridachiahydropyrone utilizing the model membrane systems as biomimetic reaction media.
ISBN: 9783319220697
Standard No.: 10.1007/978-3-319-22069-7doiSubjects--Topical Terms:
486817
Natural products
--Synthesis.
LC Class. No.: QD415.P69
Dewey Class. No.: 572
Synthetic and biophysical studies on the tridachiahydropyrone family of natural products[electronic resource] /
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Introduction -- Synthesis of the Tridachiahydropyrones and their Biomimetic Precursors -- Interactions of the Tridachiahydropyrones with Model Membrane Systems: Biophysical Studies -- Investigations into the Photoprotective and Antioxidant Properties of the Tridachiahydropyrones -- Summary and Conclusions -- Experimental -- Synthesis of Alkenyl Nitriles by the Palladium-Catalysed Cyanation of Vinyl Halides with Acetone Cyanohydrin.
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