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Advances in DNA sequence specific ag...
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  • Advances in DNA sequence specific agents[electronic resource] /
  • 紀錄類型: 書目-語言資料,印刷品 : Monograph/item
    杜威分類號: 572.8/633
    書名/作者: Advances in DNA sequence specific agents/ series editor, Graham B. Jones ; volume editor, Brant J. Chapman.
    出版者: Amsterdam, the Netherlands : : Elseview Science B.V.,, c2002.
    面頁冊數: viii, 151 p. : : ill. ;; 25 cm.
    標題: DNA.
    標題: Nucleotide sequence.
    標題: Sequence Analysis, DNA.
    ISBN: 9780444510969
    ISBN: 0444510966
    書目註: Includes bibliographical references.
    摘要、提要註: This series encompasses design, synthesis, application, and analytical methods (including clinical and in vitro) for the study of these critical interactions. As our understanding of the genome and proteome expands, general developments in the field of DNA sequence specific interaction are likely to play an increasingly important role. Accordingly, manuscripts have been solicited from experts covering a diverse range of fields, reflecting the cross-disciplinary and dynamic nature of the series. Volume 4 describes work on the modification of DNA by AT specific anticancer drugs, DNA alkylation events which involve metabolite generation, DNA sequence recognition by two selective binders, bulged DNA microenvironments as molecular targets, DNA sequence specific binding by short peptides and the analysis of DNA-protein interactions using DNase I footprinting methodology. Features include: • Expert contributors from the Biomedical world • Emerging areas of drug design and therapeutic applications • Nucleic acid-protein interactions • Color graphics of molecular modeling analyses • New and emerging methodologies.
    電子資源: http://www.sciencedirect.com/science/book/9780444510969
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